A case-referent (control) study will be performed utilizing clinically diagnosed cases of Alzheimer's disease in order to evaluate an etiologic association with occupational exposure to solvents and/or lead. The cases will consist of all males ages thirty to sixty-five at time of first diagnosis. Occupational and sociological information will be obtained by questionnaire from closest living relative or acquaintance. A matched-pairs analysis will be performed to test the hypothesis that males with occupational exposure to solvents and/or lead are at increased risk of developing presenile dementia of the Alzheimer's type.
| Shalat, S L; Seltzer, B; Baker Jr, E L (1988) Occupational risk factors and Alzheimer's disease: a case-control study. J Occup Med 30:934-6 |
| Shalat, S L; Seltzer, B; Pidcock, C et al. (1987) Risk factors for Alzheimer's disease: a case-control study. Neurology 37:1630-3 |
