Support is requested for a community wide experiment to critically assess the current state-of-the-art in the prediction of protein structure from sequence (CASP). The experiments for which funding is requested will cover CASP6-CASP8, i.e. the sixth to eighth such experiments in a series. Previous experiments were held biannually from 1994-2002. A total of over 300 groups have submitted over 80,000 individual predictions to all CASP meetings. The goal of CASP is to provide an in-depth and objective assessment of our current abilities, and to assess progress since the last experiment. CASP is undoubtedly the major event in the field of structure prediction, in the sense that all groups who impacted this field significantly over the last decade have participated in this experiment. CASP also offers an excellent opportunity for training newcomers in sequence analysis. ? ?
| Moult, John; Fidelis, Krzysztof; Kryshtafovych, Andriy et al. (2011) Critical assessment of methods of protein structure prediction (CASP)--round IX. Proteins 79 Suppl 10:1-5 |
| Moult, John; Fidelis, Krzysztof; Kryshtafovych, Andriy et al. (2009) Critical assessment of methods of protein structure prediction - Round VIII. Proteins 77 Suppl 9:1-4 |
| Moult, John; Fidelis, Krzysztof; Kryshtafovych, Andriy et al. (2007) Critical assessment of methods of protein structure prediction-Round VII. Proteins 69 Suppl 8:3-9 |
| Moult, John (2006) Rigorous performance evaluation in protein structure modelling and implications for computational biology. Philos Trans R Soc Lond B Biol Sci 361:453-8 |
| Moult, John (2005) A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction. Curr Opin Struct Biol 15:285-9 |
| Moult, John; Fidelis, Krzysztof; Rost, Burkhard et al. (2005) Critical assessment of methods of protein structure prediction (CASP)--round 6. Proteins 61 Suppl 7:3-7 |
