Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Academic Research Enhancement Awards (AREA) (R15)
Project #
7R15AA013575-02
Application #
6684574
Study Section
Alcohol and Toxicology Subcommittee 4 (ALTX)
Program Officer
Lucas, Diane
Project Start
2002-07-01
Project End
2006-06-30
Budget Start
2003-01-21
Budget End
2006-06-30
Support Year
2
Fiscal Year
2002
Total Cost
$138,180
Indirect Cost
Name
University of Wyoming
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
069690956
City
Laramie
State
WY
Country
United States
Zip Code
82071
Turdi, Subat; Yuan, Ming; Leedy, Gail M et al. (2012) Chronic social stress induces cardiomyocyte contractile dysfunction and intracellular Ca2+ derangement in rats. Physiol Behav 105:498-509
Zhang, Yingmei; Ren, Jun (2011) ALDH2 in alcoholic heart diseases: molecular mechanism and clinical implications. Pharmacol Ther 132:86-95
Hom, Erik F Y; Witman, George B; Harris, Elizabeth H et al. (2011) A unified taxonomy for ciliary dyneins. Cytoskeleton (Hoboken) 68:555-65
Turdi, Subat; Fan, Xiujuan; Li, Ji et al. (2010) AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction. Aging Cell 9:592-606
Ceylan-Isik, Asli F; McBride, Shawna M; Ren, Jun (2010) Sex difference in alcoholism: who is at a greater risk for development of alcoholic complication? Life Sci 87:133-8
Zhang, Bingfang; Turdi, Subat; Li, Quan et al. (2010) Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3beta, and PTEN. Free Radic Biol Med 49:1238-53
Guo, Rui; Ren, Jun (2010) Alcohol and acetaldehyde in public health: from marvel to menace. Int J Environ Res Public Health 7:1285-301
Li, Qun; Hueckstaedt, Lindsay K; Ren, Jun (2009) The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase. Exp Physiol 94:984-94
Ren, Jun; Wold, Loren E (2008) Mechanisms of alcoholic heart disease. Ther Adv Cardiovasc Dis 2:497-506
Ren, Jun (2007) Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models. Novartis Found Symp 285:69-76;discussion 76-9, 198-9

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