Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Academic Research Enhancement Awards (AREA) (R15)
Project #
7R15EY013113-06
Application #
9320638
Study Section
Special Emphasis Panel (ZRG1-MDCN-R (96)A)
Program Officer
Shen, Grace L
Project Start
2000-07-01
Project End
2017-01-31
Budget Start
2016-08-01
Budget End
2017-01-31
Support Year
6
Fiscal Year
2014
Total Cost
$214,453
Indirect Cost
$76,983

  Institution

Name
University of Delaware
Department
Other Health Professions
Type
Schools of Allied Health Profes
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716

  Publications

Patel, Meera J; Yilmaz, Gulden; Bhatia, Lavesh et al. (2018) Site-specific fluorescence double-labeling of proteins and analysis of structural changes in solution by Fluorescence Resonance Energy Transfer (FRET). MethodsX 5:419-430
Wangtiraumnuay, Nutsuchar; Capasso, Jenina; Tsukikawa, Mai et al. (2018) Novel ABCA4 mutation leads to loss of a conserved C-terminal motif: implications for predicting pathogenicity based on genetic testing. Eur J Ophthalmol 28:123-126
Biswas-Fiss, Esther E; Affet, Stephanie; Ha, Malissa et al. (2012) Retinoid binding properties of nucleotide binding domain 1 of the Stargardt disease-associated ATP binding cassette (ABC) transporter, ABCA4. J Biol Chem 287:44097-107
Biswas-Fiss, Esther E; Kurpad, Deepa S; Joshi, Kinjalben et al. (2010) Interaction of extracellular domain 2 of the human retina-specific ATP-binding cassette transporter (ABCA4) with all-trans-retinal. J Biol Chem 285:19372-83
Biswas-Fiss, Esther E (2006) Interaction of the nucleotide binding domains and regulation of the ATPase activity of the human retina specific ABC transporter, ABCR. Biochemistry 45:3813-23
Biswas-Fiss, Esther E (2003) Functional analysis of genetic mutations in nucleotide binding domain 2 of the human retina specific ABC transporter. Biochemistry 42:10683-96
Suarez, Tatiana; Biswas, Subhasis B; Biswas, Esther E (2002) Biochemical defects in retina-specific human ATP binding cassette transporter nucleotide binding domain 1 mutants associated with macular degeneration. J Biol Chem 277:21759-67
Biswas, E E (2001) Nucleotide binding domain 1 of the human retinal ABC transporter functions as a general ribonucleotidase. Biochemistry 40:8181-7
Biswas, E E; Biswas, S B (2000) The C-terminal nucleotide binding domain of the human retinal ABCR protein is an adenosine triphosphatase. Biochemistry 39:15879-86