The long-term objective of the research is to significantly advance our understanding of nucleic acid structure, thermodynamics, and kinetics. The immediate objective of the proposed research is to significantly enhance the experimental and theoretical capability for the study of RNA folding dynamics, which are inherently linked to RNA function. RNA folding is not well understood despite RNA
Public Health Relevance
The proposed research centers on significantly enhancing the capability to study RNA folding dynamics, which is inherently linked to RNA function, through the development of multi-spectroscopic, site- specific (MS3) probes. RNA folding is not well understood despite RNA
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