The impact of psychological trauma on the population is significant. Research suggests that as many as 60.7% of men and 51.2% of women in America have been exposed to at least one extreme stressor or traumatizing event during the course of their lives. For those who develop chronic reactions to the traumatic events, the impact is considerable. Among the concerns are cognitive biases towards generalized and persistent negative appraisals. The scope of this problem is quite broad and likely includes negative evaluations of themselves, of others, and of the world. In the past, this has been captured in the diagnostic criteria of hypervigilance and a sense of foresohrtened future. These symptoms both reflect an appreciation for the ongoing sense of threat that many carry with them after trauma. More recently, the proposed criteria for the DSM-V have included a new symptom, namely persistent and exaggerated negative expectations about one's self, others, or the world in recognition of the central role negative appraisals and expectations play in the lives of some trauma survivors. In this proposal with intend to use event-related potentials (ERPs) and eye tracking technology to investigate the neurophysiological and behavioral correlates of expectancy biases and avoidance in traumatized individuals. Study Design: The project will involve the participation of 90 individuals who vary in their trauma history and PTSD status. All participants will undergo a thorough diagnostic evaluation to assess the extent of trauma and current psychopathology. The diagnostic evaluation will be followed by an assessment which will take a multi-method approach to evaluating expectancy bias including self report measures, event-related potentials (e.g., brain waves), and eye tracking technology. Objective: The overall goal of this project is the better understand how trauma and PTSD impact on expectancy in the trauma survivor. This project will achieve this goal by answering questions such as 1) Does trauma alone affect expectancies or is PTSD necessary? 2) Are expectancy biases reflected in underlying brain activity? 3) Do expectancy biases predict behaviors such as hypervigilance? 4) Do individuals engage visual and cognitive vigilance in order to initiate behavioral avoidance? This proposal reflects an important continuation and extension of previous work by this group on attentional bias after trauma.
Changes in cognitions, particularly changes in negative appraisals and expectations, occur commonly in individuals exposed to a traumatic event. This study will use event related potentials and eye tracking technology to better understand negative expectancies and possible avoidance, in traumatized individuals. The study has relevance to the scientific understanding and clinical treatment of negative expectancies which have long been thought to play a key role in posttraumatic pathology.
| Schreger, Cade; Kimble, Matthew (2017) Assessing civilian perceptions of combat veterans: An IAT study. Psychol Trauma 9:12-18 |
| Kimble, Matthew; Boxwala, Mariam; Bean, Whitney et al. (2014) The impact of hypervigilance: evidence for a forward feedback loop. J Anxiety Disord 28:241-5 |
| Kimble, Matthew O; Fleming, Kevin; Bennion, Kelly A (2013) Contributors to hypervigilance in a military and civilian sample. J Interpers Violence 28:1672-92 |
| Kimble, Matthew; Batterink, Laura; Marks, Elizabeth et al. (2012) Negative expectancies in posttraumatic stress disorder: neurophysiological (N400) and behavioral evidence. J Psychiatr Res 46:849-55 |
| Kimble, Matthew O; Fleming, Kevin; Bandy, Carole et al. (2010) Eye tracking and visual attention to threating stimuli in veterans of the Iraq war. J Anxiety Disord 24:293-9 |
| Kimble, Matthew O; Fleming, Kevin; Bandy, Carole et al. (2010) Attention to novel and target stimuli in trauma survivors. Psychiatry Res 178:501-6 |
| Kimble, Matthew O; Frueh, B Christopher; Marks, Libby (2009) Does the modified Stroop effect exist in PTSD? Evidence from dissertation abstracts and the peer reviewed literature. J Anxiety Disord 23:650-5 |
