The proposed study will be based on the continuation and expansion of the culturally-appropriate smoking cessation community intervention begun with San Francisco Hispanics in 1988. The community intervention has been based on promoting smoking cessation among current smokers and motivating non-smokers to help smokers quit. Free distribution of a Spanish language self-help smoking cessation guide (Guia Para Dejar de Fumar) has been the principal intervention component. The intervention has made wide use of electronic and printed media, established a presence in the community, offered free smoking cessation groups, and promoted available services to health providers practicing in the Hispanic community. We now propose continuation of the intervention for five more years with an expansion of its components to include prevention of smoking initiation among Hispanic adolescents and prevention of smoking relapse among smokers who quit. In order to develop culturally appropriate smoking prevention interventions targeting Hispanic adolescents, we will conduct a cross-cultural study to identify factors involved in initiation of smoking. This study will compare responses of 300 Hispanic and 150 White non-hispanic adolescents to a structured questionnaire addressing smoking experimentation and initiation. Data being collected now from smokers who quit and subsequently have relapsed will be analyzed in order to develop a more intense relapse prevention component. The association of increased depressive symptoms and current smoking, especially among Hispanic women, will also need to be addressed in the expansion of the intervention. The community intervention will be evaluated by annual cross-sectional surveys of 2000 Hispanics in San Francisco with comparisons to two baseline surveys completed in 1986-- 87. Given that the content of intervention is primarily in Spanish, less acculturated Hispanics will also be compared to more acculturated Hispanics. A cohort of current and former smokers will be recruited from the cross-sectional samples and followed prospectively with annual interviews to determine smoking behavior. Self-reported quitters will be validated with saliva cotinine.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Demonstration and Dissemination Projects (R18)
Project #
5R18CA039260-10
Application #
2089801
Study Section
Special Emphasis Panel (SRC (J1))
Project Start
1985-06-01
Project End
1996-05-31
Budget Start
1994-06-01
Budget End
1996-05-31
Support Year
10
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Benowitz, Neal L; Perez-Stable, Eliseo J; Herrera, Brenda et al. (2002) Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans. J Natl Cancer Inst 94:108-15
Posner, S F; Stewart, A L; Marin, G et al. (2001) Factor variability of the Center for Epidemiological Studies Depression Scale (CES-D) among urban Latinos. Ethn Health 6:137-44
Benowitz, N L; Perez-Stable, E J; Fong, I et al. (1999) Ethnic differences in N-glucuronidation of nicotine and cotinine. J Pharmacol Exp Ther 291:1196-203
Perez-Stable, E J; Herrera, B; Jacob 3rd, P et al. (1998) Nicotine metabolism and intake in black and white smokers. JAMA 280:152-6
Perez-Stable, E J; Marin, G; Posner, S F (1998) Ethnic comparison of attitudes and beliefs about cigarette smoking. J Gen Intern Med 13:167-74
Munoz, R F; Marin, B V; Posner, S F et al. (1997) Mood management mail intervention increases abstinence rates for Spanish-speaking Latino smokers. Am J Community Psychol 25:325-43
Marin, G; Perez-Stable, E J (1995) Effectiveness of disseminating culturally appropriate smoking-cessation information: Programa Latino Para Dejar de Fumar. J Natl Cancer Inst Monogr :155-63
Perez-Stable, E J; Benowitz, N L; Marin, G (1995) Is serum cotinine a better measure of cigarette smoking than self-report? Prev Med 24:171-9
Perez-Stable, E J; Marin, G; Marin, B V (1994) Behavioral risk factors: a comparison of Latinos and non-Latino whites in San Francisco. Am J Public Health 84:971-6
Marin, B V; Perez-Stable, E J; Marin, G et al. (1994) Effects of a community intervention to change smoking behavior among Hispanics. Am J Prev Med 10:340-7

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