The long-term aim of this proposal is to develop and validate an effective case management approach for people with dual diagnoses of substance abuse and chronic mental illness. New Hampshire's treatment program for dually diagnosed clients centers on the continuous treatment team-- a model which combines the principles of assertive case management and integrated treatment for substance abuse and mental illness. Continuous treatment teams will be compared with standard case management in community support programs. case management functioning will be assessed with several quantitative measures--a case manger service/activity log, MIS data, a measure of work environment, and case manager characteristics--as well as an ethnographic approach. This project will develop and maintain a continuous treatment team in the state largest city, Manchester, with the aid of an established public-academic liaison and an extensive training program for dual diagnosis clinicians. The first objective of the project is to decrease the problems most characteristic of dual diagnosis clients: alcohol and drug abuse, housing instability and homelessness, and institutionalization in hospitals and jails. A second objective is to determine whether good outcomes in these primary domains will be associated with more general improvements in symptoms, functional status, and quality of life. a third objective is to clarify pathways into and out of homelessness in this highly vulnerable population. A fourth objective is to identify the qualities of case management that are associated with successful engagement and treatment of dual diagnosis clients. Separate data analysis strategies will be applied to each of these objectives. The research evaluation design is a randomized clinical trial in Manchester and five other clinical sites, three of which are rural. A total of 270 consenting dual diagnosis clients will be randomly assigned to either continuous treatment teams or to standard case management. Study subjects will be interviewed with standard quantitative instruments at baseline and at six-month followup intervals for two years. A parallel ethnographic evaluation will occur at the Manchester site.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Demonstration and Dissemination Projects (R18)
Project #
1R18MH046072-01
Application #
3442769
Study Section
(SRCM)
Project Start
1989-09-30
Project End
1992-08-31
Budget Start
1989-09-30
Budget End
1990-08-31
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
NH State Department/Health Statistics/Data Mgmt
Department
Type
DUNS #
011040545
City
Concord
State
NH
Country
United States
Zip Code
03301
Xie, Haiyi; McHugo, Gregory; Sengupta, Anjana et al. (2004) A method for analyzing longitudinal outcomes with many zeros. Ment Health Serv Res 6:239-46
Xie, Haiyi; McHugo, Gregory; Drake, Robert et al. (2003) Using discrete-time survival analysis to examine patterns of remission from substance use disorder among persons with severe mental illness. Ment Health Serv Res 5:55-64
Nixon, John; Phipps, Kate; Glanville, Julie et al. (2002) Using economic evidence to support decision making: a case study of assertive community treatment within the UK National Service Framework for Mental Health. Appl Health Econ Health Policy 1:179-90
Mueser, K T; Essock, S M; Drake, R E et al. (2001) Rural and urban differences in patients with a dual diagnosis. Schizophr Res 48:93-107
Alverson, H; Alverson, M; Drake, R E (2001) Social patterns of substance use among people with dual diagnoses. Ment Health Serv Res 3:3-14
Clark, R E (2001) Family support and substance use outcomes for persons with mental illness and substance use disorders. Schizophr Bull 27:93-101
Drake, R E; Xie, H; McHugo, G J et al. (2000) The effects of clozapine on alcohol and drug use disorders among patients with schizophrenia. Schizophr Bull 26:441-9
Alverson, H; Alverson, M; Drake, R E (2000) An ethnographic study of the longitudinal course of substance abuse among people with severe mental illness. Community Ment Health J 36:557-69
McHugo, G J; Drake, R E; Teague, G B et al. (1999) Fidelity to assertive community treatment and client outcomes in the New Hampshire dual disorders study. Psychiatr Serv 50:818-24
Clark, R E; Ricketts, S K; McHugo, G J (1999) Legal system involvement and costs for persons in treatment for severe mental illness and substance use disorders. Psychiatr Serv 50:641-7

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