This application responds to PAR-95-024 which """"""""solicits exploratory/developmental research grant applications to support the secondary analysis of data relevant to the prevention of alcohol abuse and alcoholism"""""""". Alcohol abuse has been implicated as one of the negative consequences of childhood victimization (physical and sexual abuse and neglect). The data set proposed for use in this grant application overcomes many of the shortcomings of previous research and currently represents the most comprehensive, prospective, large scale, and longterm data base for addressing the consequences of early childhood victimization. The data set contains archival information from court records, official criminal history information from three levels of law enforcement at two time periods, and community level census tract information for a large sample of substantiated cases of early childhood physical and sexual abuse and neglect and matched controls (n=1,575) who were followed up and assessed. In-person follow-up interviews in young adulthood (n=1,144) obtained information on psychiatric, cognitive, intellectual, social, familial, and behavioral functioning of the respondents, as well as information on parental alcohol and drug use. Analyses will be directed toward substantive and methodological goals: (1) to test a number of hypotheses about the possible mechanisms linking childhood victimization to later alcohol problems in females; (2) to examine the co-occurrence of alcohol abuse and other psychiatric disorders in these individuals and to compare age of onset and symptom patterns among co-occurring psychiatric disorders; (3) to examine relationships among childhood victimization, alcohol abuse, and violence; (4) to examine the role of protective factors in moderating or buffering the development of alcohol abuse and alcoholism; and (5) to compare rates of alcohol abuse in individuals who retrospectively self-report childhood victimization with rates in persons with documented (official) reports of childhood victimization.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Exploratory/Developmental Grants (R21)
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Clinical and Treatment Subcommittee (ALCP)
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State University of New York at Albany
Other Domestic Higher Education
United States
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Widom, Cathy Spatz; Horan, Jacqueline; Brzustowicz, Linda (2015) Childhood maltreatment predicts allostatic load in adulthood. Child Abuse Negl 47:59-69
Horan, Jacqueline M; Widom, Cathy S (2015) From Childhood Maltreatment to Allostatic Load in Adulthood: The Role of Social Support. Child Maltreat 20:229-39
Horan, Jacqueline M; Widom, Cathy Spatz (2015) Cumulative childhood risk and adult functioning in abused and neglected children grown up. Dev Psychopathol 27:927-41
Francis, Melville M; Nikulina, Valentina; Widom, Cathy Spatz (2015) A Prospective Examination of the Mechanisms Linking Childhood Physical Abuse to Body Mass Index in Adulthood. Child Maltreat 20:203-13
Widom, Cathy Spatz; Czaja, Sally J; DuMont, Kimberly A (2015) Intergenerational transmission of child abuse and neglect: real or detection bias? Science 347:1480-5
Horan, Jacqueline M; Widom, Cathy Spatz (2015) Does age of onset of risk behaviors mediate the relationship between child abuse and neglect and outcomes in middle adulthood? J Youth Adolesc 44:670-82
Young, Joanna Cahall; Widom, Cathy Spatz (2014) Long-term effects of child abuse and neglect on emotion processing in adulthood. Child Abuse Negl 38:1369-81
Nikulina, Valentina; Widom, Cathy Spatz (2014) Do race, neglect, and childhood poverty predict physical health in adulthood? A multilevel prospective analysis. Child Abuse Negl 38:414-24
Widom, Cathy Spatz (2014) VARIETIES OF VIOLENT BEHAVOR. Criminology 52:313-344
Widom, Cathy Spatz; Czaja, Sally; Dutton, Mary Ann (2014) Child abuse and neglect and intimate partner violence victimization and perpetration: a prospective investigation. Child Abuse Negl 38:650-63

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