Alcoholics Anonymous (AA) is the most popular and widely accessed resource in the United States for individuals with alcohol problems (Room & Greenfield, 1993), and a variety of cross-sectional and prospective studies indicate such participation is beneficial (Emrick et al., 1993; Tonigan et al, 1995; 2002). Because AA provides direct access to a community-based recovery network available """"""""on demand"""""""" it possesses a unique combination of accessibility, flexibility, and cost-effectiveness that makes it a valuable public health resource for addressing alcohol problems. In spite of its prevalence and salutary influence, however, knowledge about exactly why AA is helpful (i.e. the mechanisms involved), and for whom (i.e., what factors moderate benefits), remains poorly understood and rarely investigated (Kelly, 2003). One robust finding, identified across diverse ? AA-exposed alcohol dependent individuals in different trajectories of recovery, is that increased self-efficacy explains, in part, AA-related benefits (e.g, Morgenstern et al, 1997). Unclear, however, is whether increased self-efficacy, as a change mechanism, is specific to AA, and whether the relative importance of self-efficacy differs as individuals progress in recovery. ? ? The primary aims of this secondary analysis of the large, Project MATCH, prospective clinical dataset are to address these specific knowledge gaps, with the added benefit of broadening the mechanisms of change under investigation. We also investigate potential moderators of AA's effects. In so doing, we hope to begin to elucidate pathways and dynamic processes involved in recovery that will inform the timing and content of future interventions. Specifically we will: 1) examine the relative and unique contributions of four competing sets of mediational variables in explaining AA's effects- i) AA-specific variables [step work, sponsor, spirituality], ii) AA non-specific variables [self-efficacy, motivation], iii) cognitiveaffective variables (anger, depression), and, iv) social network variables [ friends' drinking]; 2) test whether the mechanisms by which AA exerts its effects vary temporally (e.g., is affect regulation more important early in recovery and spirituality more important later?); 3) assess whether AA-exposed vs. non-exposed patients tend to use different sets of mechanisms to achieve improved outcomes; and, 4) test whether certain patient subgroups benefit more or less from AA participation (e.g., patients with axis I psychopathology). A secondary aim is to examine the process and impact of AA """"""""disaffiliation"""""""" by exploring outcomes of former AA attendees and provide information on patterns of affiliation/ disaffiliation. A further secondary aim is to investigate the relationship between AA and use of formal treatment services. Findings from this exploratory/development study will directly inform clinical interventions and provide a strong, empirical foundation from which to launch further prospective work specifically tailored to examine the broader mechanisms and processes of recovery in a mixed clinical and community sample. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21AA016762-02
Application #
7463931
Study Section
Special Emphasis Panel (ZAA1-EE (82))
Program Officer
Martinelli, Angela
Project Start
2007-07-05
Project End
2010-06-30
Budget Start
2008-07-01
Budget End
2010-06-30
Support Year
2
Fiscal Year
2008
Total Cost
$193,726
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Hoeppner, Bettina B; Hoeppner, Susanne S; Kelly, John F (2014) Do young people benefit from AA as much, and in the same ways, as adult aged 30+? A moderated multiple mediation analysis. Drug Alcohol Depend 143:181-8
Pagano, Maria E; White, William L; Kelly, John F et al. (2013) The 10-year course of Alcoholics Anonymous participation and long-term outcomes: a follow-up study of outpatient subjects in Project MATCH. Subst Abus 34:51-9
Pagano, Maria E; Kelly, John F; Scur, Michael D et al. (2013) Assessing youth participation in AA-related helping: validity of the Service to Others in Sobriety (SOS) questionnaire in an adolescent sample. Am J Addict 22:60-6
Kelly, John F; Hoeppner, Bettina B (2013) Does Alcoholics Anonymous work differently for men and women? A moderated multiple-mediation analysis in a large clinical sample. Drug Alcohol Depend 130:186-93
Kelly, John F; Hoeppner, Bettina; Stout, Robert L et al. (2012) Determining the relative importance of the mechanisms of behavior change within Alcoholics Anonymous: a multiple mediator analysis. Addiction 107:289-99
Stout, Robert L; Kelly, John F; Magill, Molly et al. (2012) Association between social influences and drinking outcomes across three years. J Stud Alcohol Drugs 73:489-97
Kelly, John F; Stout, Robert L; Magill, Molly et al. (2011) Spirituality in recovery: a lagged mediational analysis of alcoholics anonymous' principal theoretical mechanism of behavior change. Alcohol Clin Exp Res 35:454-63
Kelly, John F; Stout, Robert L; Magill, Molly et al. (2011) The role of Alcoholics Anonymous in mobilizing adaptive social network changes: a prospective lagged mediational analysis. Drug Alcohol Depend 114:119-26
Kelly, John F; Stout, Robert L; Tonigan, J Scott et al. (2010) Negative affect, relapse, and Alcoholics Anonymous (AA): does AA work by reducing anger? J Stud Alcohol Drugs 71:434-44
Kelly, John F; Stout, Robert L; Magill, Molly et al. (2010) Mechanisms of behavior change in alcoholics anonymous: does Alcoholics Anonymous lead to better alcohol use outcomes by reducing depression symptoms? Addiction 105:626-36