This study will leverage nationally-representative survey data to determine the current prevalence, severity, geographic distribution, and determinants of food allergy among the US population. In 2016, we collaborated with an expert panel of primary care physicians, allergists, epidemiologists, biostatisticians and health services researchers to develop and administer comprehensive population-based cross-sectional surveys assessing the current prevalence of food allergy among 80,000 U.S. households. The surveys were administered by the independent research organization NORC at the University of Chicago, and population-weighted results are now available for analysis. This study will analyze and interpret these nationally-representative survey data in order to determine the prevalence, distribution, and determinants of food allergy and the development of tolerance to previously allergenic foods among adults and children in the US, and to assess recent trends in childhood food allergy prevalence since our prior 2009-2010 pediatric prevalence survey. These data will be the first to characterize food allergy among adults, including adult-onset food allergy, and the development of tolerance. These data will also provide a much-needed update to our landmark 2009-2010 study of childhood food allergy, the estimates from which remain the most widely cited estimates of childhood food allergy prevalence in the US. Furthermore these data will permit a comprehensive look into current FA diagnosis and management trends, and will determine the degree to which current clinical and self-management practices are consistent with those recommended by the 2010 NIAID-sponsored Guidelines for the Diagnosis and Management of Food Allergy. Findings from the present study will increase our understanding of the interplay of socio-environmental and individual factors on the development of new-onset food allergy and the development of tolerance among adults and children. By characterizing current FA, we will inform the context of future food allergy research regarding diagnosis, management, and treatment of this rapidly emerging, multi-generational health concern.

Public Health Relevance

This study will analyze and disseminate survey data collected from concurrent nationally representative samples of 40,000 children and 40,000 adults in order to determine the current prevalence, severity, and distribution of food allergy among the US population. These findings will improve our understanding of the interplay of socio-environmental and individual factors on the development of new-onset food allergy and the development of tolerance among adults and children. By characterizing the current population-level food allergy burden in the US, and trends in pediatric prevalence since 2009-2010, we will inform the context of future food allergy research regarding diagnosis, management, and treatment of this rapidly emerging, multi- generational health concern.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21AI135702-02
Application #
9614886
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Davidson, Wendy F
Project Start
2017-12-15
Project End
2020-11-30
Budget Start
2018-12-01
Budget End
2020-11-30
Support Year
2
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Children's Memorial Hospital (Chicago)
Department
Type
DUNS #
074438755
City
Chicago
State
IL
Country
United States
Zip Code
60611