The transition to adult HIV care is often accompanied by reduced medication adherence, retention, HIV viral load suppression and CD4 cell counts; however, little is known about which interventions might be most effective in supporting adolescents undergoing this care transition. We will conduct a feasibility study for a community-based accompaniment intervention, delivered by community health workers, that is designed to improve health outcomes among adolescents transitioning to adult care in urban Peru. We will (1) conduct an intervention pilot to determine the feasibility of an accompaniment intervention designed to improved retention with viral load suppression (i.e., ?successful transition?) among a diverse cohort of adolescents living with HIV; (2) pilot study procedures relevant to a future intervention trial; and (3) conduct a retrospective chart review to collect data to inform recruitment and sample size calculations for a future intervention trial.

Public Health Relevance

The transition to adult HIV care is often accompanied by reduced medication adherence, retention, HIV viral load suppression and CD4 cell counts; however, little is known about which interventions might be most effective in supporting adolescents undergoing this care transition. In a diverse cohort of adolescents living with HIV in Peru, we will examine the feasibility of a time-limited community-based accompaniment intervention designed to improve clinical and behavioral outcomes throughout the transition period.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21AI143365-02
Application #
9886206
Study Section
AIDS Clinical Studies and Epidemiology Study Section (ACE)
Program Officer
Miller, Judith A
Project Start
2019-03-05
Project End
2021-02-28
Budget Start
2020-03-01
Budget End
2021-02-28
Support Year
2
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Harvard Medical School
Department
Other Health Professions
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115