This R21 project is designed to explore the potential for information storage in water clusters, or aggregates, which could constitute the molecular basis for homeopathic practice. The possibility that information could be stored in water aggregates has been implicit in past work, albeit controversial. Recently, it was demonstrated that water is impacted by various surfaces in a profound way: The water adjacent to the surface excludes large solutes, and the solute-exclusion zone is much larger than anticipated (Zheng and Pollack, 2003); hence considerable water is involved. More recent studies show that the solute-exclusion zone has a character different from that of ordinary water, and that it is stable for extended periods. Hence, the possibility exists that such water might carry long-term information about the molecular structure to which it had been exposed. The proposed studies will explore this possibility. They will pursue two specific aims: first, to determine whether such water aggregates can remain intact for the long term when the original nucleation surface is removed; and, second, to determine whether these aggregates contain information about the surface. If the hypothesis is supported and confirmed by more extensive studies, it may provide a vehicle for understanding why solutions with compounds that are extremely diluted can have biological effects not unlike those in high concentration.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21AT002635-01A1
Application #
6968278
Study Section
Special Emphasis Panel (ZAT1-DB (18))
Program Officer
Wong, Shan S
Project Start
2005-09-30
Project End
2007-08-31
Budget Start
2005-09-30
Budget End
2006-08-31
Support Year
1
Fiscal Year
2005
Total Cost
$189,569
Indirect Cost
Name
University of Washington
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Musumeci, Francesco; Pollack, Gerald H (2012) Influence of water on the work function of certain metals. Chem Phys Lett 536:65-67
Chai, B; Mahtani, A G; Pollack, G H (2012) UNEXPECTED PRESENCE OF SOLUTE-FREE ZONES AT METAL-WATER INTERFACES. Contemp Mater 3:1-12
Ovchinnikova, Kate; Pollack, Gerald H (2009) Cylindrical phase separation in colloidal suspensions. Phys Rev E Stat Nonlin Soft Matter Phys 79:036117
Zheng, Jian-Ming; Chin, Wei-Chun; Khijniak, Eugene et al. (2006) Surfaces and interfacial water: evidence that hydrophilic surfaces have long-range impact. Adv Colloid Interface Sci 127:19-27