. The long-term goal of our parent research program is to document how the gastrointestinal (GI) tract transduces luminal signals to the brain via peripheral nerves and how these nerves modulate GI sensory function. The goal of this US-Japan BRPC administrative supplement is for Dr. Diego Bohrquez (parent grant P.I) who is a neuroscientist at Duke University (Durham, NC, USA) to visit Dr. Michael Huffman who is a primate behaviorist at the Primate Research Institute of Kyoto University (Nagoya, Japan). The goal of the visit is to acquire advanced research skills and start to conduct collaborative research to uncover the neural basis of self-medication. In particular, and related to the goals of the R21AT010818 NIH-NCCIH parent grant ?The efferent synapse in enteroendocrine cells?, the visit will have two specific aims: 1. To learn the scientific methodology used to study self-medication in primates in the field at the Primate Research Institute. 2. To identify potential medicinal plants and compounds to test back at Duke University. Once characterized these compounds could be used to alleviated behavioral disorders by targeting gut sensory function. By learning how self-medicating behaviors are identified and studied in the wild, we will be able to translate that work to our laboratory. Moreover, by identifying plants with medicinal values, these compounds could be used to modulate gut sensory function in an effort to treat behavioral disorders by modulating gut sensory function.

Public Health Relevance

This US-Japan BRPC administrative supplement is for Dr. Diego Bohrquez (parent grant PI), who is a neuroscientist at Duke University (Durham, NC, USA), to visit Dr. Michael Huffman, who is a primate behaviorist at the Primate Research Institute of Kyoto University (Nagoya, Japan). The goal of the visit is to acquire research skills pertaining to self-medication.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Exploratory/Developmental Grants (R21)
Project #
3R21AT010818-02S1
Application #
10258314
Study Section
Program Officer
Chen, Wen G
Project Start
2019-09-16
Project End
2021-08-31
Budget Start
2021-01-13
Budget End
2021-08-31
Support Year
2
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705