Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21CA069851-02
Application #
2113820
Study Section
Special Emphasis Panel (SRC (06))
Project Start
1995-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Urology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Bhattacharyya, Rumi S; Stern, Paula H (2003) IGF-I and MAP kinase involvement in the stimulatory effects of LNCaP prostate cancer cell conditioned media on cell proliferation and protein synthesis in MC3T3-E1 osteoblastic cells. J Cell Biochem 90:925-37
Gann, P H; Chatterton, R T; Lee, C (2001) Peptide growth factors as biomarkers of prostate cancer risk. Epidemiol Rev 23:67-71
Kassen, A E; Sensibar, J A; Sintich, S M et al. (2000) Autocrine effect of DHT on FGF signaling and cell proliferation in LNCaP cells: role of heparin/heparan-degrading enzymes. Prostate 44:124-32
Engel, J D; Kundu, S D; Yang, T et al. (1999) Transforming growth factor-beta type II receptor confers tumor suppressor activity in murine renal carcinoma (Renca) cells. Urology 54:164-70
Gann, P H; Klein, K G; Chatterton, R T et al. (1999) Growth factors in expressed prostatic fluid from men with prostate cancer, BPH, and clinically normal prostates. Prostate 40:248-55
Sintich, S M; Lamm, M L; Sensibar, J A et al. (1999) Transforming growth factor-beta1-induced proliferation of the prostate cancer cell line, TSU-Pr1: the role of platelet-derived growth factor. Endocrinology 140:3411-5
Sintich, S M; Steinberg, J; Kozlowski, J M et al. (1999) Cytotoxic sensitivity to tumor necrosis factor-alpha in PC3 and LNCaP prostatic cancer cells is regulated by extracellular levels of SGP-2 (clusterin). Prostate 39:87-93
Zhu, N; Pewitt, E B; Cai, X et al. (1998) Calreticulin: an intracellular Ca++-binding protein abundantly expressed and regulated by androgen in prostatic epithelial cells. Endocrinology 139:4337-44
Kundu, S D; Kim, I Y; Zelner, D et al. (1998) Absence of expression of transforming growth factor-beta type II receptor is associated with an aggressive growth pattern in a murine renal carcinoma cell line, Renca. J Urol 160:1883-8
Lamm, M L; Long, D D; Goodwin, S M et al. (1997) Transforming growth factor-beta1 inhibits membrane association of protein kinase C alpha in a human prostate cancer cell line, PC3. Endocrinology 138:4657-64

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