Smoking is the leading preventable cause of death and disease in the U.S. Each year approximately 30% of smokers try to quit, with the vast majority of attempts (~90%) ending in relapse. This is complicated by treatment barriers related to cost and accessibility. Identifying cost effective ways to aide in cessation success, which can be widely disseminated, remains vitally important. According to the dual-process model of substance use, addiction develops via an imbalance between effortful control and automatic psychological processes. The affective processing model suggests that during withdrawal, automatic psychological processes increase implicit drug seeking motivation. Implicit motivation is hypothesized as the underlying mechanism through which automatic psychological processes exert control over behavior. Research suggests that behavioral impulse control may attenuate the association between implicit motivation and substance use. Response inhibition, one form of behavioral impulse control, is the ability to inhibit behavioral responses to salient approach cues. Smokers tend to have less behavioral impulse control. In addition, poor behavioral impulse control makes individuals more vulnerable to various risk factors associated with relapse (e.g., positive expectancies, higher craving during abstinence, etc.). Improving smoking relevant behavioral impulse control may affect multiple indices of relapse. Research in cognitive retraining has shown that response inhibition can be modified through training. Recently this has been extended to training using mobile devices. The development of mobile interventions which specifically target underlying mechanisms of addiction may provide a novel adjunct to current cessation programs. The current proposal builds on previous research by implementing a response inhibition training paradigm in the context of a cessation trial. It is hypothesized that this task will reduce the likelihood of relapse following a quit attempt. Furthermore, it is hypothesized that training effects will operate via decreases in implicit motivation and global craving. If successful, the current study will provide evidence for a relapse prevention tool that can (1) increase overall cessation success and (2) be widely and easily dispersed.

Public Health Relevance

This project seeks to decrease the likelihood of relapse during a quit attempt by modifying smoking specific behavioral response inhibition using mobile technology. If successful this project will provide evidence for a scientifically supported cessation application that can be downloaded to mobile devices (e.g., smartphones) through mobile marketplaces. The ability to widely disseminate a scientifically valid application that increases the likely of cessation success could have significant public health implications.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21DA035761-01A1
Application #
8701611
Study Section
Risk, Prevention and Intervention for Addictions Study Section (RPIA)
Program Officer
Grossman, Debra
Project Start
2014-05-15
Project End
2016-04-30
Budget Start
2014-05-15
Budget End
2015-04-30
Support Year
1
Fiscal Year
2014
Total Cost
Indirect Cost
Name
North Dakota State University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Fargo
State
ND
Country
United States
Zip Code
58108
Dvorak, Robert D; Stevenson, Brittany L; Kilwein, Tess M et al. (2018) Tension reduction and affect regulation: An examination of mood indices on drinking and non-drinking days among university student drinkers. Exp Clin Psychopharmacol 26:377-390
Dvorak, Robert D; Troop-Gordon, Wendy; Stevenson, Brittany L et al. (2018) A randomized control trial of a deviance regulation theory intervention to increase alcohol protective strategies. J Consult Clin Psychol 86:1061-1075
Dvorak, Robert D; Waters, Andrew J; MacIntyre, Jessica M et al. (2018) Affect, craving, and cognition: An EMA study of ad libitum adolescent smoking. Psychol Addict Behav 32:583-594