Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21DK057497-01
Application #
2884649
Study Section
Endocrinology Study Section (END)
Program Officer
Haft, Carol Renfrew
Project Start
1999-09-01
Project End
2001-08-31
Budget Start
1999-09-01
Budget End
2000-08-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Toledo
Department
Physiology
Type
Schools of Medicine
DUNS #
807418939
City
Toledo
State
OH
Country
United States
Zip Code
43614
Park, So-Young; Cho, You-Ree; Kim, Hyo-Jeong et al. (2006) Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1. Am J Physiol Endocrinol Metab 291:E517-24
Wisloff, Ulrik; Najjar, Sonia M; Ellingsen, Oyvind et al. (2005) Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science 307:418-20
Najjar, Sonia M; Yang, Yan; Fernstrom, Mats A et al. (2005) Insulin acutely decreases hepatic fatty acid synthase activity. Cell Metab 2:43-53
McInerney, Marcia F; Najjar, Sonia M; Brickley, Deanna et al. (2004) Anti-insulin receptor autoantibodies are not required for type 2 diabetes pathogenesis in NZL/Lt mice, a New Zealand obese (NZO)-derived mouse strain. Exp Diabesity Res 5:177-85
Dai, Tong; Abou-Rjaily, George A; Al-Share', Qusai Y et al. (2004) Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice. J Biol Chem 279:45155-61
Abou-Rjaily, George A; Lee, Sang Jun; May, Denisa et al. (2004) CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation. J Clin Invest 114:944-52
Phan, Dillon; Cheng, Chien-Jui; Galfione, Matthew et al. (2004) Identification of Sp2 as a transcriptional repressor of carcinoembryonic antigen-related cell adhesion molecule 1 in tumorigenesis. Cancer Res 64:3072-8
Northcott, Carrie A; Poy, Matthew N; Najjar, Sonia M et al. (2002) Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats. Circ Res 91:360-9
Najjar, Sonia M (2002) Regulation of insulin action by CEACAM1. Trends Endocrinol Metab 13:240-5
Poy, Matthew N; Ruch, Randall J; Fernstrom, Mats A et al. (2002) Shc and CEACAM1 interact to regulate the mitogenic action of insulin. J Biol Chem 277:1076-84

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