Millions of Americans undergo urinary catheterization annually. Catheter-related urinary tract infection (DTI) is the most common infection seen in long-term care facilities and a common source of septicemia, which results in death for 2 of every 10 patients. Yet there are no prospective studies in a nationally representative sample of Americans that enumerate the risk of UTI and septicemia in residents of long-term care facilities. Nor are there population-based studies of the determinants and consequences of such risk. This study was designed to address these issues.
The first aim of this study is to describe use of urinary collection devices in a cohort of residents in long-term care facilities and determine the antecedent factors and effects of such use. The Long Term Care Minimum Data Set for California, Texas, New York, Florida, and Michigan, years 2002-2003, will be utilized. The selected states represent 34.9% of the elderly population in the United States.
The second aim i s to determine the risks, both incident and recurrent, of UTI and septicemia by bladder management strategy in residents of long-term care facilities. Hospitalization rates due to UTI and septicemia will also be ascertained. A population-based cohort study will be conducted, using linked databases containing information from the Long Term Care Minimum Data Set and Medicare data from acute care hospitals in California, Texas, New York, Florida, and Michigan, years 2002-2003. The Minimum Data Set has information on the physical functioning, health conditions, medical diagnoses, activities of daily living, cognition, sensory and communication patterns, behavior, diet, activity patterns, psychosocial wellbeing, and background of each patient, so that individuals at greater risk of infection or hospitalization can be identified. This investigation would be the first population-based study to characterize those individuals at higher risk of UTI and septicemia in long-term care facilities in the United States. This will provide valuable baseline information for surveillance purposes, preventive efforts, and health care planning. Since approximately 40% of elderly Americans will enter a nursing home at some point, identification of those at risk of infection could have considerable health, quality of life, and economic consequences.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21DK067451-01A1
Application #
6917381
Study Section
Special Emphasis Panel (ZRG1-HOP-N (90))
Program Officer
Eggers, Paul Wayne
Project Start
2005-06-01
Project End
2007-05-31
Budget Start
2005-06-01
Budget End
2006-05-31
Support Year
1
Fiscal Year
2005
Total Cost
$153,000
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Rogers, Mary A M; Mody, Lona; Chenoweth, Carol et al. (2008) Incidence of antibiotic-resistant infection in long-term residents of skilled nursing facilities. Am J Infect Control 36:472-5
Rogers, Mary A M; Mody, Lona; Kaufman, Samuel R et al. (2008) Use of urinary collection devices in skilled nursing facilities in five states. J Am Geriatr Soc 56:854-61
Rogers, Mary A M; Fries, Brant E; Kaufman, Samuel R et al. (2008) Mobility and other predictors of hospitalization for urinary tract infection: a retrospective cohort study. BMC Geriatr 8:31
Watts, Brook; Argekar, Pushkar; Saint, Sanjay et al. (2007) Clinical problem-solving. Building a diagnosis from the ground up--a 49-year-old man came to the clinic with a 1-week history of suprapubic pain and fever. N Engl J Med 356:1456-62
Rogers, Mary A M; Blumberg, Neil; Saint, Sanjay K et al. (2006) Allogeneic blood transfusions explain increased mortality in women after coronary artery bypass graft surgery. Am Heart J 152:1028-34
Shojania, Kaveh G; Fletcher, Kathlyn E; Saint, Sanjay (2006) Graduate medical education and patient safety: a busy--and occasionally hazardous--intersection. Ann Intern Med 145:592-8
Hollingsworth, John M; Rogers, Mary A M; Kaufman, Samuel R et al. (2006) Medical therapy to facilitate urinary stone passage: a meta-analysis. Lancet 368:1171-9