Abstract

The Duke University Eye Center, the Division of Biometry, and the Duke Clinical Research Institute propose to develop a Clinical Vision Research Unit which will provide national leadership in the design, coordination and conduct of clinical research and clinical trials with the goal of improving the understanding, prevention and treatment of visual system disorders. To this end, the specific aims of the project are: (1) to recruit a Ph.D. statistician who will provide the methodological and statistical expertise for the Unit; (2) to enhance the clinical vision research capabilities of the faculty in the Clinical Vision Research Unit; (3) develop a physical facility that will facilitate the clinical activities of the Unit; (4) to design and conduct clinical research studies which will improve our understanding of the cause of vision disorders; (5) to design NIH-and industry-sponsored clinical trials for the treatment of vision disorders and to serve as a coordinating center for these trials.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21EY011725-04
Application #
6179234
Study Section
Special Emphasis Panel (ZEY1-VSN (01))
Program Officer
Everett, Donald F
Project Start
1997-04-01
Project End
2002-03-30
Budget Start
2000-04-01
Budget End
2001-03-31
Support Year
4
Fiscal Year
2000
Total Cost
$115,500
Indirect Cost

  Institution

Name
Duke University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Mruthyunjaya, Prithvi; Khalatbari, Dara; Yang, Ping et al. (2006) Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis. Arch Ophthalmol 124:1012-8
Mruthyunjaya, Prithvi; Stinnett, Sandra S; Toth, Cynthia A (2005) Impact of fluorescein angiographic characteristics of macular lesions on outcomes after macular translocation 360 degree surgery in eyes with age-related macular degeneration. Retina 25:597-607
Cahill, Mark T; Stinnett, Sandra S; Banks, Avie D et al. (2005) Quality of life after macular translocation with 360 degrees peripheral retinectomy for age-related macular degeneration. Ophthalmology 112:144-51
Song, Julia; Lee, Paul P; Epstein, David L et al. (2005) High failure rate associated with 180 degrees selective laser trabeculoplasty. J Glaucoma 14:400-8
Ray, Robin; Stinnett, Sandra S; Jaffe, Glenn J (2005) Evaluation of image artifact produced by optical coherence tomography of retinal pathology. Am J Ophthalmol 139:18-29
Reeves, Sherman W; Stinnett, Sandra; Adelman, Ron A et al. (2005) Risk factors for progression to penetrating keratoplasty in patients with keratoconus. Am J Ophthalmol 140:607-11
Cahill, Mark T; Banks, Avie D; Stinnett, Sandra S et al. (2005) Vision-related quality of life in patients with bilateral severe age-related macular degeneration. Ophthalmology 112:152-8
Mruthyunjaya, Prithvi; Stinnett, Sandra S; Toth, Cynthia A (2004) Change in visual function after macular translocation with 360 degrees retinectomy for neovascular age-related macular degeneration. Ophthalmology 111:1715-24
Li, Junping; Herndon, Leon W; Asrani, Sanjay G et al. (2004) Clinical comparison of the Proview eye pressure monitor with the Goldmann applanation tonometer and the Tonopen. Arch Ophthalmol 122:1117-21
Tseng, Wendy; Cortez, Rafael T; Ramirez, Gema et al. (2004) Prevalence and risk factors for proliferative vitreoretinopathy in eyes with rhegmatogenous retinal detachment but no previous vitreoretinal surgery. Am J Ophthalmol 137:1105-15

Showing the most recent 10 out of 13 publications