Children of depressed mothers are at significant risk for depression and other psychiatric disorders, poor social and emotional adjustment, and increased problem behaviors. Given the significant negative personal and social consequences of depression, it is important to gain an understanding of early risk mechanisms that lead to adverse child outcomes. The proposed study examines the patterns of autobiographical memory retrieval in young children of depressed mothers that may contribute to their vulnerabilities to depression. Although past research has focused on overgeneral autobiographical memory as a potential marker of vulnerability to depression in adults, little is known about how this problematic memory retrieval pattern emerges and develops, and how overgeneral autobiographical memory is related to future problems in children. In the proposed study, 3.5- to 4-year-old children of depressed (n = 60) and nondepressed (n = 60) mothers will be recruited and followed over a 9-month period. We seek to understand 1) how maternal factors (maternal depression, overgeneral autobiographical memory, reminiscing quality) and child factors (self-representation, executive function, and gender) affect children?s autobiographical memory specificity; 2) how children?s overgeneral autobiographical memory predicts early markers of childhood depression; and 3) whether child overgeneral autobiographical memory mediates the link between maternal factors and early markers of childhood depression. Should the goals of this study be met, the findings would be informative to early prevention efforts in reducing the risk for adverse outcomes among children of depressed mothers.

Public Health Relevance

Much evidence has cumulated to show that adults with clinical depression or elevated depressive symptoms retrieve more overgeneral autobiographical memory than nondepressed individuals. However, little empirical research has focused on overgeneral autobiographical memory as a potential risk mechanism that leads to vulnerabilities to depression in children. The proposed study examines whether and how overgeneral autobiographical memory in preschool-age children may serve as a pathway that links maternal depression with early markers of childhood depression.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21HD095179-01A1
Application #
9600879
Study Section
Child Psychopathology and Developmental Disabilities Study Section (CPDD)
Program Officer
Esposito, Layla E
Project Start
2018-09-01
Project End
2020-08-31
Budget Start
2018-09-01
Budget End
2019-08-31
Support Year
1
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Ohio State University
Department
Miscellaneous
Type
Schools of Education
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210