Hurricane Maria made landfall in Puerto Rico (PR) on September 20, 2017 as Category 5 storm, killing at least 64 people and causing an estimated $90 billion in damage. Cancer patients are particularly vulnerable to the devastation caused by Maria; it is estimated that 90% of patients have experienced interruptions in their care. The current study will describe unmet medical and psychological needs as well as barriers and facilitators to care in cancer patients in PR. In addition, Maria presents a unique opportunity to study the intersection of stress and cancer, specifically the impact of extreme physical and mental stress on hypothalamic-pituitary-adrenal (HPA) axis functioning which is known to affect cancer biology.
Study aims are to: 1) to describe unmet medical and psychological needs over time among cancer patients in PR affected by Hurricane Maria, 2) to identify multilevel barriers and facilitators to access to care, and 3) to explore putative physiological markers of stress in patients and a matched sample of non-cancer controls affected by Hurricane Maria. The current study leverages a longstanding U54-funded partnership between Ponce Health Sciences University (PHSU) and Moffitt Cancer Center. Resources include an Community Outreach Core and the Puerto Rico Biobank as well as a history of collaboration among members of the research team.

Public Health Relevance

Cancer patients are particularly vulnerable to the devastation caused by Hurricane Maria; it is estimated that 90% of patients have experienced interruptions in their care. The current study will describe unmet medical and psychological needs as well as barriers and facilitators to care in cancer patients in PR. In addition, exposure to Hurricane Maria presents a unique opportunity to study the intersection of stress and cancer, specifically the impact of extreme physical and mental stress on hypothalamic-pituitary-adrenal (HPA) axis functioning which is known to affect cancer biology.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21MD013674-01
Application #
9686263
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Alvidrez, Jennifer L
Project Start
2018-09-17
Project End
2020-05-31
Budget Start
2018-09-17
Budget End
2019-05-31
Support Year
1
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Ponce School of Medicine
Department
Type
DUNS #
105742043
City
Ponce
State
PR
Country
United States
Zip Code