This application describes a novel and innovative program of research designed to examine the therapeutic applications of virtual reality (VR) technology to solve the problem of generalizability of social skills training (SST) for children with higher functioning autism (HFA). Several studies indicate that SST has the potential to significantly improve the adaptive behaviors and quality of life of HFA children. However, cost and safety issues have prevented SST intervention paradigms from including effective methods to practice and generalize social skills beyond the immediate contexts of intervention. Therefore, the problem of generalizability currently impedes progress on the development of optimally effective SST programs for HFA children. One potential means for addressing this problem is to apply advances in VR technology to provide social skills practice environments for HFA children. VR environments may provide HFA children with varied but more controlled and safer social contexts, than are available in """"""""real life"""""""", to practice social skills exercises that maximize learning while minimizing risks of failure and negative reinforcement learning ((McGeorge et al. 2001;Parsons et al. 2006;Standen &Brown, 2005). Therefore, a major aim of the R21 phase of this application is to bring together expertise in the study of virtual social interactions with expertise in the clinical science of autism to develop VR social skills practice tasks that may be used to augment current SST intervention methods for HFA children. A goal of the R33 phase is to provide an initial randomized case control test of the effectiveness of VR augmentation of SST with 42 HFA children between the ages of 8 and 18. The R33 phase of research will also be designed to provide empirical tests of novel hypotheses about measures of executive self monitoring and motivation associated with behavioral activation t may predict individual differences in responsiveness of HFA to treatment (Mundy et al. 2007). It is anticipated that the results of this program of research will support the development of a larger randomized controlled efficacy study of VR augmented SST for HFA children. The results will also support larger theory based examinations of the factors that affect individual differences in intervention responsiveness in autism. In addition, although the initial therapeutic focus of this research will be on SST for HFA children it is reasonable to expect that the general principles, procedures and VR intervention platforms developed in the course of this research will have the potential for widespread, cost-effective applications to interventions for a variety of other neuro- developmental disorders (e.g. ADHD) across a range of context (i.e. home, clinics and schools).

Public Health Relevance

Much of the current focus on intervention for autism focuses on the treatment of children with autism and mental retardation in the preschool period. However, without a commensurate level of treatment research specific to the needs of HFA children a significant problem of continuity of care has developed and the long- term outcomes for many of these children remain poor. This application proposes to assist in addressing this problem with an integration of therapeutic applications of virtual reality technology with proven methods of social skills training to develop a treatment to better address the outstanding mental health care needs of higher functioning children with autism.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21MH085904-02
Application #
7897781
Study Section
Special Emphasis Panel (ZMH1-ERB-L (02))
Program Officer
Gilotty, Lisa
Project Start
2009-08-01
Project End
2012-07-31
Budget Start
2010-08-01
Budget End
2012-07-31
Support Year
2
Fiscal Year
2010
Total Cost
$176,185
Indirect Cost
Name
University of California Davis
Department
Type
Organized Research Units
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Mundy, Peter; Novotny, Stephanie; Swain-Lerro, Lindsey et al. (2017) Joint-Attention and the Social Phenotype of School-Aged Children with ASD. J Autism Dev Disord 47:1423-1435
Kim, Kwanguk; Rosenthal, M Zachary; Gwaltney, Mary et al. (2015) A Virtual Joy-Stick Study of Emotional Responses and Social Motivation in Children with Autism Spectrum Disorder. J Autism Dev Disord 45:3891-9
Jarrold, William; Mundy, Peter; Gwaltney, Mary et al. (2013) Social attention in a virtual public speaking task in higher functioning children with autism. Autism Res 6:393-410
Kim, Kwanguk; Mundy, Peter (2012) Joint attention, social-cognition, and recognition memory in adults. Front Hum Neurosci 6:172
Mundy, Peter; Jarrold, William (2010) Infant joint attention, neural networks and social cognition. Neural Netw 23:985-97
Mundy, Peter; Gwaltney, Mary; Henderson, Heather (2010) Self-referenced processing, neurodevelopment and joint attention in autism. Autism 14:408-29