Many individuals with cancer experience multiple, co-occurring symptoms that drastically impair functioning and quality of life. The process of trying to manage multiple symptoms can be overwhelming to patients. An innovative approach to patient education has recently been developed that should facilitate the process of managing multiple symptoms9. This proposal represents the first phase in the process of applying the representational approach to a new delivery mode (from in-person interviews to correspondence via secure internet messaging services) and to a more complex patient care situation (from management of a single, pre-determined symptom to multiple, patient-selected symptoms). We refer to this as a Written Representational intervention To Ease Symptoms, or WRITE symptoms.
The specific aims of this pilot study, conducted in collaboration with the National Ovarian Cancer Coalition (NOCC), are to conduct preliminary evaluations (feasibility, acceptability, and initial efficacy) of WRITE symptoms with a sample of women with recurrent ovarian cancer. Subjects will be 90 women experiencing two or more bothersome symptoms associated with ovarian cancer recruited via mailed invitations and advertisements on the NOCC website. Women will be randomly assigned to one of 2 conditions: 1) a full baseline assessment, WRITE symptoms intervention group; and 2) a full baseline assessment, modified wait-list control group. WRITE symptoms will be delivered via secure messaging services situated on the NOCC website. Measures of symptom representations, symptom interference with life activities and quality of life will be completed by all subjects at baseline and 5 and 9 weeks later. Assessment of feasibility and acceptability will be conducted during recruitment, throughout the study period, and after subjects have completed the study. Should WRITE symptoms pass initial evaluations of feasibility, acceptability, and efficacy, knowledge gained from this pilot study will be used to plan a randomized controlled trial grant application (R01) to determine the efficacy of the intervention and the potential mechanism(s) through which the intervention has its effect.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21NR009275-01A1
Application #
6967219
Study Section
Nursing Science: Adults and Older Adults Study Section (NSAA)
Program Officer
Hare, Martha L
Project Start
2005-08-15
Project End
2007-07-31
Budget Start
2005-08-15
Budget End
2006-07-31
Support Year
1
Fiscal Year
2005
Total Cost
$222,750
Indirect Cost
Name
University of Pittsburgh
Department
Other Health Professions
Type
Schools of Nursing
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Donovan, Heidi S; Ward, Sandra E; Sereika, Susan M et al. (2014) Web-based symptom management for women with recurrent ovarian cancer: a pilot randomized controlled trial of the WRITE Symptoms intervention. J Pain Symptom Manage 47:218-30
Donovan, Heidi S; Kwekkeboom, Kristine L; Rosenzweig, Margaret Q et al. (2009) Nonspecific effects in psychoeducational intervention research. West J Nurs Res 31:983-98
Dumrongpakapakorn, Phensiri; Hopkins, Kathy; Sherwood, Paula et al. (2009) Computer-mediated patient education: opportunities and challenges for supporting women with ovarian cancer. Nurs Clin North Am 44:339-54
Donovan, Heidi Scharf; Ward, Sandra E; Song, Mi-Kyung et al. (2007) An update on the representational approach to patient education. J Nurs Scholarsh 39:259-65