Non-communicable diseases (NCDs), including diabetes and hypertension, are becoming grave emerging health threats in sub-Saharan Africa, especially among people living with HIV. The health of people living with NCDs and HIV could be significantly improved through interventions encouraging behavioral lifestyle changes, and family-based interventions to enact such change show exciting promise. However, little research has been conducted on these conditions and on interventions to address them in sub-Saharan Africa. In contrast, HIV has been extensively researched and has become a chronic condition in these settings. Due to the existing, well-developed infrastructure of HIV-related services and the commonalities in providing long-term care for HIV and NCDs, developing interventions that integrate screening and care for non-communicable diseases with HIV care is needed. However, more needs to be understood on the prevalence and risk factors of these conditions prior to developing an effective, feasible intervention. Therefore, this mixed methods study seeks to (1) establish the prevalence and risk factors of diabetes and hypertension among people receiving HIV-related care in urban Tanzania and (2) understand families? knowledge, beliefs, and actions relating to diabetes and hypertension and how this can lead to implementing a family-centered intervention to improve health for this population. To realize these objectives, we propose screening 364 clients receiving HIV-related care for diabetes and hypertension and conducting further assessments with a sub-set of clients? families. Within 40 families, we will conduct home-based screening for diabetes and hypertension for all adult family members. These families will also be interviewed to assess their understanding of diabetes and hypertension, how the family environment contributes to NCD risks, and how the family can be used to increase support and decrease NCD risks for people living with HIV. Results from this study will be used to develop and test a relevant, culturally-appropriate family-based intervention to improve patient health outcomes for HIV and NCDs.

Public Health Relevance

Non-communicable diseases (NCDs), including diabetes and hypertension, are a growing problem in sub- Saharan Africa, and NCDs are especially problematic for people living with HIV due to certain interactions with anti-retroviral medication. Finding ways to integrate care and support for HIV and NCDs is of paramount importance to public health. This project is an exploratory study to understand the prevalence and risk factors of diabetes and hypertension among people living with HIV and their families and to understand how to design and implement an effective family-centered intervention that could improve health outcomes for both HIV and NCDs.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21TW010482-02
Application #
9356594
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Levintova, Marya
Project Start
2016-09-01
Project End
2019-06-30
Budget Start
2017-07-01
Budget End
2019-06-30
Support Year
2
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Psychiatry
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29403