Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Unknown (R22)
Project #
5R22AI022442-03
Application #
3444819
Study Section
Bacteriology and Mycology Subcommittee 1 (BM)
Project Start
1984-12-01
Project End
1987-11-30
Budget Start
1986-12-01
Budget End
1987-11-30
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
National Hansen's Disease Program
Department
Type
DUNS #
City
Baton Rouge
State
LA
Country
United States
Zip Code
70816
Adams, L B; Gillis, T P; Hwang, D H et al. (1997) Effects of essential fatty acid deficiency on prostaglandin E2 production and cell-mediated immunity in a mouse model of leprosy. Infect Immun 65:1152-7
Adams, L B; Fukutomi, Y; Krahenbuhl, J L (1993) Regulation of murine macrophage effector functions by lipoarabinomannan from mycobacterial strains with different degrees of virulence. Infect Immun 61:4173-81
Ramasesh, N; Adams, L B; Franzblau, S G et al. (1991) Effects of activated macrophages on Mycobacterium leprae. Infect Immun 59:2864-9
Sibley, L D; Adams, L B; Fukutomi, Y et al. (1991) Tumor necrosis factor-alpha triggers antitoxoplasmal activity of IFN-gamma primed macrophages. J Immunol 147:2340-5
Adams, L B; Franzblau, S G; Vavrin, Z et al. (1991) L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae. J Immunol 147:1642-6
Adams, L B; Hibbs Jr, J B; Taintor, R R et al. (1990) Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine. J Immunol 144:2725-9
Sibley, L D; Adams, L B; Krahenbuhl, J L (1990) Inhibition of interferon-gamma-mediated activation in mouse macrophages treated with lipoarabinomannan. Clin Exp Immunol 80:141-8
Ramasesh, N; Krahenbuhl, J L; Hastings, R C (1989) In vitro effects of antimicrobial agents on Mycobacterium leprae in mouse peritoneal macrophages. Antimicrob Agents Chemother 33:657-62
Hastings, R C; Gillis, T P; Krahenbuhl, J L et al. (1988) Leprosy. Clin Microbiol Rev 1:330-48
Sibley, L D; Krahenbuhl, J L (1988) Induction of unresponsiveness to gamma interferon in macrophages infected with Mycobacterium leprae. Infect Immun 56:1912-9

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