This research will investigate the effects of two different methods of postsurgical intermaxillary fixation techniques on short-term stability of the surgically advanced mandile using Macaca mulatta as experimental subjects. Stabililty of the distal segment of the madible after sagittal ramus advancement osteotomy using 1) dental intermaxillary fixation, and 2) dental plus skeletal intermaxillary fixation will be studied cephalometrically in twenty adult female Macaca mulatta. Adaptations within the periodontal ligament and alveolar bone will be evaluated histologically at several intervals of time postsurgically to determine whether differences between the two experimental groups occurs. Adaptations within the suprahyoid musculature will be evaluated cephalometrically, histologically, and electromyographically. The short-term effects of intermaxillary fixation on the adult mandibular condyle will be evaluated histologically. The results of this study will have a direct and immediate impact on the related clinical problem of relapse after mandibular advancement surgery and will direct the choice of intermaxillary fixation techniques employed in the future.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Unknown (R23)
Project #
5R23DE006874-02
Application #
3447079
Study Section
Oral Biology and Medicine Study Section (OBM)
Project Start
1984-03-01
Project End
1987-02-28
Budget Start
1985-03-01
Budget End
1986-02-28
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Ellis 3rd, E; Carlson, D S; Billups, J (1992) Osseous healing of the sagittal ramus osteotomy: a histologic comparison of rigid and nonrigid fixation in Macaca mulatta. J Oral Maxillofac Surg 50:718-23
Ellis 3rd, E; Hinton, R J (1991) Histologic examination of the temporomandibular joint after mandibular advancement with and without rigid fixation: an experimental investigation in adult Macaca mulatta. J Oral Maxillofac Surg 49:1316-27
Ellis 3rd, E; Dechow, P C; Carlson, D S et al. (1990) Electromyography of the suprahyoid musculature following mandibular advancement with and without rigid fixation. J Oral Maxillofac Surg 48:49-53
Mayo, K H; Ellis 3rd, E; Carlson, D S (1990) Histochemical analysis of the masseter and temporalis muscles in macaca mulatta after mandibular advancement using rigid or nonrigid fixation. J Oral Maxillofac Surg 48:381-4
Ellis 3rd, E; Carlson, D S (1989) The effects of mandibular immobilization on the masticatory system. A review. Clin Plast Surg 16:133-46
Carlson, D S; Ellis 3rd, E; Dechow, P C et al. (1989) Short-term stability and muscle adaptation after mandibular advancement surgery with and without suprahyoid myotomy in juvenile Macaca mulatta. Oral Surg Oral Med Oral Pathol 68:135-49
Reynolds, S T; Ellis 3rd, E; Carlson, D S (1988) Adaptation of the suprahyoid muscle complex to large mandibular advancements. J Oral Maxillofac Surg 46:1077-85
Ellis 3rd, E; Reynolds, S; Carlson, D S (1988) Stability of the mandible following advancement: a comparison of three postsurgical fixation techniques. Am J Orthod Dentofacial Orthop 94:38-49
Ellis 3rd, E; Dechow, P C; Carlson, D S (1988) A comparison of stimulated bite force after mandibular advancement using rigid and nonrigid fixation. J Oral Maxillofac Surg 46:26-32
Ellis 3rd, E (1988) Mobility of the mandible following advancement and maxillomandibular or rigid internal fixation: an experimental investigation in Macaca mulatta. J Oral Maxillofac Surg 46:118-23

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