The research proposed is designed to identify and characterize metabolic benefits of an amino acid formula enriched with branched chain amino acids (BCAA) compared with a balanced amino acid mixture in the nutritional support of injury metabolism. The paired studies described would utilize a controlled, reproducible human model of injury metabolism. Specifically they would: 1. determine the relative efficiency of BCAA enriched and balanced amino acid mixtures in achieving nitrogen equilibrium during induced injury metabolism; 2. characterize the metabolic alterations induced in this model when nitrogen equilibrium was maintained both with BCAA enriched and balanced amino acid mixtures; 3. determine differences in those responses noted above (#2) that could be attributed to the composition of the nitrogen source.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Unknown (R23)
Project #
5R23GM034019-02
Application #
3447876
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1984-07-01
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294