Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Unknown (R23)
Project #
5R23HL033860-02
Application #
3448818
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1985-06-01
Project End
1986-07-31
Budget Start
1986-06-01
Budget End
1986-07-31
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
New York University
Department
Type
Schools of Medicine
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
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Ferreira Jr, O C; Valinsky, J E; Sheridan, K et al. (1991) Phorbol ester-induced differentiation of U937 cells enhances attachment to fibronectin and distinctly modulates the alpha 5 beta 1 and alpha 4 beta 1 fibronectin receptors. Exp Cell Res 193:20-6
Garcia-Pardo, A; Wayner, E A; Carter, W G et al. (1990) Human B lymphocytes define an alternative mechanism of adhesion to fibronectin. The interaction of the alpha 4 beta 1 integrin with the LHGPEILDVPST sequence of the type III connecting segment is sufficient to promote cell attachment. J Immunol 144:3361-6
Ferreira Jr, O C; Garcia-Pardo, A; Bianco, C (1990) Specific binding of the human monocytic cell line U937 to the alternatively spliced connecting segment (IIICS) of fibronectin. J Exp Med 171:351-6
Garcia-Pardo, A; Ferreira, O C (1990) Adhesion of human T-lymphoid cells to fibronectin is mediated by two different fibronectin domains. Immunology 69:121-6
Garcia-Pardo, A; Ferreira, O C; Valinsky, J et al. (1989) Fibronectin receptors of mononuclear phagocytes: binding characteristics and biochemical isolation. Exp Cell Res 181:420-31
Garcia-Pardo, A; Rostagno, A; Frangione, B (1987) Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity. Biochem J 241:923-8
Rostagno, A; Frangione, B; Pearlstein, E et al. (1986) Fibronectin binds to amyloid P component. Localization of the binding site to the 31,000 dalton C-terminal domain. Biochem Biophys Res Commun 140:12-20