Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Resource-Related Research Projects (R24)
Project #
3R24CA083148-03S1
Application #
6535690
Study Section
Special Emphasis Panel (ZCA1-SRRB-9 (M1))
Program Officer
Croft, Barbara
Project Start
1999-09-01
Project End
2004-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
3
Fiscal Year
2002
Total Cost
$62,307
Indirect Cost
Name
University of Arizona
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Moore, Jared W; Barrett, Harrison H; Furenlid, Lars R (2009) Adaptive CT for High-Resolution, Controlled-Dose, Region-of-Interest Imaging. IEEE Nucl Sci Symp Conf Rec (1997) 2009:4154-4157
Morse, David L; Carroll, Danielle; Day, Sam et al. (2009) Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway. NMR Biomed 22:114-27
Vargas, Gracie; Barton, Jennifer K; Welch, Ashley J (2008) Use of hyperosmotic chemical agent to improve the laser treatment of cutaneous vascular lesions. J Biomed Opt 13:021114
Morse, David L; Galons, Jean-Philippe; Payne, Claire M et al. (2007) MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms. NMR Biomed 20:602-14
Morse, David L; Raghunand, Natarajan; Sadarangani, Pooja et al. (2007) Response of choline metabolites to docetaxel therapy is quantified in vivo by localized (31)P MRS of human breast cancer xenografts and in vitro by high-resolution (31)P NMR spectroscopy of cell extracts. Magn Reson Med 58:270-80
Jordan, Benedicte F; Black, Kvar; Robey, Ian F et al. (2005) Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo. NMR Biomed 18:430-9
Liu, Zhonglin; Stevenson, Gail D; Barrett, Harrison H et al. (2005) Imaging recognition of inhibition of multidrug resistance in human breast cancer xenografts using 99mTc-labeled sestamibi and tetrofosmin. Nucl Med Biol 32:573-83
Jordan, Benedicte F; Runquist, Matthew; Raghunand, Natarajan et al. (2005) Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478. Neoplasia 7:475-85
Jordan, Benedicte F; Runquist, Matthew; Raghunand, Natarajan et al. (2005) The thioredoxin-1 inhibitor 1-methylpropyl 2-imidazolyl disulfide (PX-12) decreases vascular permeability in tumor xenografts monitored by dynamic contrast enhanced magnetic resonance imaging. Clin Cancer Res 11:529-36
Morse, David L; Carroll, Danielle; Weberg, Lyndon et al. (2005) Determining suitable internal standards for mRNA quantification of increasing cancer progression in human breast cells by real-time reverse transcriptase polymerase chain reaction. Anal Biochem 342:69-77

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