We propose to continue and expand a successful series of interdisciplinary collaborations currently funded as the P-50 Michigan Interdisciplinary Center on Social Inequalities, Mind, and Body. Consistent with the change from a P50 to an R24 Center, the MICSIMB will emphasize support cores for funded research projects, research enhancements to these projects, and exploratory/pilot studies. The R-24 MICSIMB will support the expansion of an innovative interdisciplinary research program seeking to understand the relationships of psychosocial factors related to health (beliefs, attitudes, affective states, values, stress and social relationships), their broader social, community, and psychological antecedents, and the pathophysiologic pathways through which psychosocial factors and their antecedents contribute to the development of physical and mental disorders. The research will encompass human development over the full life course from infancy and childhood through adulthood and older age, consider a broad range of physical and mental health outcomes, with some emphasis on aging, human development, and cardiovascular disease, and have important foci on health disparities, life course approaches, spatial analysis/neighborhood effects, gene-environment interaction, and methodological innovation. The research enhancements will make use of a large set of ongoing activities and archived data available at the University of Michigan, representing information on diverse, representative study populations of over 200,000 people. The activities cover a range of topics from analysis of the role of neighborhood and community factors and psychosocial factors in health, to interactions between genes and the socioeconomic and psychosocial environment in hypertension and dementia. Such an approach will build on the previous efforts of a large number of studies and represents a very cost-effective approach to addressing critical issues in the expanded program of mind-body research that we have been carrying on so successfully. Participating will be a very accomplished interdisciplinary group of 22 core investigators, spanning 16 units across the University who have published over 1,000 scientific papers that have been cited more than 22,000 times with at least 85% of these papers relevant to the proposed Center expansion.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Resource-Related Research Projects (R24)
Project #
3R24HD047861-02S1
Application #
7110838
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Spittel, Michael
Project Start
2004-09-27
Project End
2009-08-31
Budget Start
2005-09-01
Budget End
2006-08-31
Support Year
2
Fiscal Year
2005
Total Cost
$53,692
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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Knittel, Andrea K; Snow, Rachel C; Riolo, Rick L et al. (2015) Modeling the community-level effects of male incarceration on the sexual partnerships of men and women. Soc Sci Med 147:270-9
Johnson-Lawrence, V; Kaplan, G; Galea, S (2015) Socio-economic patterning in adulthood and depressive symptoms among a community sample of older adults in the United States. Public Health 129:594-6
Johnson-Lawrence, Vicki; Galea, Sandro; Kaplan, George (2015) Cumulative socioeconomic disadvantage and cardiovascular disease mortality in the Alameda County Study 1965 to 2000. Ann Epidemiol 25:65-70
Johnson-Lawrence, Vicki; Kaplan, George; Galea, Sandro (2013) Socioeconomic mobility in adulthood and cardiovascular disease mortality. Ann Epidemiol 23:167-71
Mair, Christina; Kaplan, George A; Everson-Rose, Susan A (2012) Are there hopeless neighborhoods? An exploration of environmental associations between individual-level feelings of hopelessness and neighborhood characteristics. Health Place 18:434-9
Paczkowski, Magdalena M; Kruk, Margaret E; Tessema, Fasil et al. (2012) Depressive symptoms and posttraumatic stress disorder as determinants of preference weights for attributes of obstetric care among Ethiopian women. PLoS One 7:e46788
Do, D Phuong; Diez Roux, Ana V; Hajat, Anjum et al. (2011) Circadian rhythm of cortisol and neighborhood characteristics in a population-based sample: the Multi-Ethnic Study of Atherosclerosis. Health Place 17:625-32
Dowd, Jennifer B; Ranjit, Nalini; Do, D Phuong et al. (2011) Education and levels of salivary cortisol over the day in US adults. Ann Behav Med 41:13-20
Dowd, Jennifer B; Albright, Jeremy; Raghunathan, Trivellore E et al. (2011) Deeper and wider: income and mortality in the USA over three decades. Int J Epidemiol 40:183-8

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