The goal of this proposal is to transform UTMB into a center of rigorous high quality comparative effectiveness research (CER) and patient-centered outcomes research (PCOR), focused on healthcare decision-making facing older individuals, their providers, and the health systems providing their care. Achieving this goal requires an institution-wide commitment to the following specific aims: 1) Establish structures for ongoing participation of key stakeholder groups and the larger community. 2) Training and education in PCOR of investigators, clinical leaders, providers, administrators &students. 3) Establish a robust infrastructure for sustainable growth and productivity in PCOR/CER. 4) Conduct rigorous PCOR relevant to aging. 5) Disseminate findings from PCOR/CER generated at UTMB and at other centers to the UTMB communities, and to stakeholders regionally and nationally. 6) Ongoing, active evaluation of all our efforts, to allow for modifications. The thematic research focus of this proposal is aging. Our planned programs will evaluate and compare healthcare delivery systems, as well as design, test and disseminate novel interventions to improve decision making. Important goals of this work are to include on-going input and collaboration with patients and other stakeholders, and to identify or develop systems that reduce racial, ethnic and age-associated disparities in health outcomes using patient-centered approaches. We have secured active partnership with key organizations and leaders within UTMB, including substantial institutional support for new faculty positions in PCOR. In addition, we are partnering with several established centers of excellence in key aspects of PCOR, including the Evidence-based Practice Centers at the University of Minnesota and Oregon, and the John M. Eisenberg Center for Clinical Decisions and Communication Sciences at Baylor. We will also partner with the other University of Texas Health Science campuses and regional health professions schools in disseminating PCOR.

National Institute of Health (NIH)
Agency for Healthcare Research and Quality (AHRQ)
Resource-Related Research Projects (R24)
Project #
Application #
Study Section
Health Care Quality and Effectiveness Research (HQER)
Program Officer
Moore, Jennifer E
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Fiscal Year
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University of Texas Medical Br Galveston
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Singh, Gurinder; Agarwal, Amitesh; Zhang, Wei et al. (2018) Impact of PAP therapy on hospitalization rates in Medicare beneficiaries with COPD and coexisting OSA. Sleep Breath :
Chaaban, Mohamad R; Zhang, Dong; Resto, Vicente et al. (2018) Factors influencing recurrent emergency department visits for epistaxis in the elderly. Auris Nasus Larynx 45:760-764
Raji, Mukaila A; Kuo, Yong-Fang; Adhikari, Deepak et al. (2018) Decline in opioid prescribing after federal rescheduling of hydrocodone products. Pharmacoepidemiol Drug Saf 27:513-519
Middleton, Addie; Kuo, Yong-Fang; Graham, James E et al. (2018) Readmission Patterns Over 90-Day Episodes of Care Among Medicare Fee-for-Service Beneficiaries Discharged to Post-acute Care. J Am Med Dir Assoc 19:896-901
Mehta, Hemalkumar B; Sura, Sneha D; Adhikari, Deepak et al. (2018) Adapting the Elixhauser comorbidity index for cancer patients. Cancer 124:2018-2025
Kuo, Yong-Fang; Adhikari, Deepak; Eke, Chiemeziem G et al. (2018) Processes and Outcomes of Congestive Heart Failure Care by Different Types of Primary Care Models. J Card Fail 24:9-18
Housten, Ashley J; Pappadis, Monique R; Krishnan, Shilpa et al. (2018) Resistance to discontinuing breast cancer screening in older women: A qualitative study. Psychooncology 27:1635-1641
Kuo, Yong-Fang; Raji, Mukaila A; Liaw, Victor et al. (2018) Opioid Prescriptions in Older Medicare Beneficiaries After the 2014 Federal Rescheduling of Hydrocodone Products. J Am Geriatr Soc 66:945-953
Hoover, Diana S; Pappadis, Monique R; Housten, Ashley J et al. (2018) Preferences for Communicating about Breast Cancer Screening Among Racially/Ethnically Diverse Older Women. Health Commun :1-5
Cary Jr, Michael P; Hall, Rasheeda K; Anderson, Amber L et al. (2018) Management Team Perceptions of Risks and Strategies for Preventing Falls Among Short-Stay Patients in Nursing Homes. Health Care Manag (Frederick) 37:76-85

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