We propose creating an integrated Center for patient-centered outcomes research (PCOR) and comparative effectiveness research (CER) at the University of Texas Southwestern Medical Center in Dallas (UTSW), Parkland Health and Hospital System (Parkland), Children's Medical Center (Children's), and the North Texas Veterans Administration Health Systems (Dallas VA). The theme of the Center is PCOR/CER in underserved patients, populations, and settings, including those served by safety net systems. We will leverage the resources at UTSW, Parkland, Children's, Dallas VA, UTSW CTSA and all UTSW academic institutions, and broadly engage stakeholders needed to achieve the following aims: 1. Develop the infrastructure and programs to increase expertise and research activity in PCOR/CER. 2. Create formal education, training, mentorship and career development activities in PCOR/CER for faculty, trainees, and students, and expand understanding of PCOR/CER across our campus. 3. Establish the structures, policies and procedures needed to support meaningful stakeholder engagement. 4. Conduct PCOR/CER to improve the outcomes of care among underserved patients and populations. 5. Disseminate findings to researchers, health systems, and local, state and national stakeholders. 6. Perform formative and summative evaluation of our progress and overcome any barriers to success. We have strong financial commitments from the leaders of all UTSW and partner institutions. Three projects will harness data in the electronic medical record to conduct observational and interventional studies to improve care for high risk, underserved patients and populations. All projects will engage stakeholders throughout the research, implementation, and dissemination process. We will partner with the AHRQ-funded Johns Hopkins University EPC and DEclDE Centers of Excellence. We will collaborate with our 5 other sister Univ. of TX Health Science Centers (in Houston, San Antonio, Galveston, Tyler) ~all who have safety net affiliates to disseminate our findings. All activities aim to promote PCOR/CER to improve the delivery of care to the underserved that is patient-centered, evidence-based, high quality, equitable, and efficient.

Public Health Relevance

Patients that are poor, minority, and lack insurance have worse outcomes. Our Center will develop, assess, and disseminate approaches to improving patient-centered care among underserved patients and populations. We will emphasize approaches that use electronic medical records to identify those at high risk of poor outcomes and system-based outreach programs to deliver high quality care to those most in need.

National Institute of Health (NIH)
Agency for Healthcare Research and Quality (AHRQ)
Resource-Related Research Projects (R24)
Project #
Application #
Study Section
Special Emphasis Panel (ZHS1-HSR-A (02))
Program Officer
Moore, Jennifer E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas Sw Medical Center Dallas
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Lee, Simon Craddock; Higashi, Robin T; Sanders, Joanne M et al. (2018) Effects of program scale-up on time to resolution for patients with abnormal screening mammography results. Cancer Causes Control 29:995-1005
Parikh, Neehar D; Scaglione, Steve; Li, Yumeng et al. (2018) A Comparison of Staging Systems for Hepatocellular Carcinoma in a Multicenter US Cohort. Clin Gastroenterol Hepatol 16:781-782
Rich, Nicole E; Oji, Stefany; Mufti, Arjmand R et al. (2018) Racial and Ethnic Disparities in Nonalcoholic Fatty Liver Disease Prevalence, Severity, and Outcomes in the United States: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 16:198-210.e2
Balasubramanian, Bijal A; Jetelina, Katelyn K; Bowen, Michael et al. (2018) Surveillance for colorectal cancer survivors in an integrated safety-net health system in the United States. Int J Care Coord 21:26-35
Makam, Anil N; Nguyen, Oanh Kieu; Xuan, Lei et al. (2018) Long-Term Acute Care Hospital Use of Non-Mechanically Ventilated Hospitalized Older Adults. J Am Geriatr Soc 66:2112-2119
Murphy, Caitlin C; Fullington, Hannah M; Alvarez, Carlos A et al. (2018) Polypharmacy and patterns of prescription medication use among cancer survivors. Cancer 124:2850-2857
Nguyen, Oanh Kieu; Higashi, Robin T; Makam, Anil N et al. (2018) The Influence of Financial Strain on Health Decision-Making. J Gen Intern Med 33:406-408
Zhang, Song; Cao, Jing; Ahn, Chul (2018) Sample size calculation for before-after experiments with partially overlapping cohorts. Contemp Clin Trials 64:274-280
Makris, Una E; Ferrante, Lauren E; Mody, Lona (2018) Leadership Lessons: Building and Nurturing a High-Performing Clinical Research Team. J Am Geriatr Soc 66:1258-1261
Bowen, Michael E; Bhat, Deepa; Fish, Jason et al. (2018) Improving Performance on Preventive Health Quality Measures Using Clinical Decision Support to Capture Care Done Elsewhere and Patient Exceptions. Am J Med Qual 33:237-245

Showing the most recent 10 out of 89 publications