EXCEED THE SPACE PROVIDED. This revised Meharry MRISP application requests support for the development of an increased capability of Meharry faculty and students to conduct highly competitive and rigorous mental health research. To achieve this goal we aim to accomplish four specific measurable objectives which are to: 1)Increase the scholarly productivity of center participants by 10% each year for each of the next five years; 2) Increase the number of mainstream grants, with mental health relatedness, acquired by center faculty by 10% each year over the next five years; 3) To develop and acquire funding for a formal interdisciplinary training program in neuroscience by FY '02; 4) To develop a minimumof two funded neuroscience/mental health relevant research grants directed by principal investigators in clinical departments. To accomplish the four measurable objectives we have proposed a program of administrative support, infrastructural support, and transitional research support. To ensure the accomplishment of the measurable objectives we have established and will implement a comprehensive plan of evaluation. The successful implementation of this proposal will result in the development of a marked increased capacity of Meharry faculty and students to engage in competitive and rigorous mental health research. An additional expected outcome is that Meharry will expand its role as a major producer of well trained African American neuroscience Ph.D.'s. This outcome will assist in the national effort to more fully develop the nation's humanresource pool. PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Resource-Related Research Projects (R24)
Project #
5R24MH057067-08
Application #
6884587
Study Section
Special Emphasis Panel (ZMH1-BRB-P (03))
Program Officer
Mays, Robert A
Project Start
1997-05-01
Project End
2008-04-30
Budget Start
2005-05-01
Budget End
2008-04-30
Support Year
8
Fiscal Year
2005
Total Cost
$545,661
Indirect Cost
Name
Meharry Medical College
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
041438185
City
Nashville
State
TN
Country
United States
Zip Code
37208
Ivy, Michael T; Newkirk, Robert F; Wang, Yilun et al. (2010) A novel choline cotransporter sequestration compartment in cholinergic neurons revealed by selective endosomal ablation. J Neurochem 112:1295-304
McCallister, Monique M; Maguire, Mark; Ramesh, Aramandla et al. (2008) Prenatal exposure to benzo(a)pyrene impairs later-life cortical neuronal function. Neurotoxicology 29:846-54
Williams, Shimere; Mmbaga, Natu; Chirwa, Sanika (2006) Dopaminergic D1 receptor agonist SKF 38393 induces GAP-43 expression and long-term potentiation in hippocampus in vivo. Neurosci Lett 402:46-50
Cao, Z; Wang, Y; McAdory, B S et al. (2006) Identification and characterization of syntaxin 1 antisense variants in Limulus polyphemus. Cell Mol Neurobiol 26:53-66
Chirwa, Sanika; Aduonum, Adwoa; Pizarro, Jose et al. (2005) Dopaminergic DA1 signaling couples growth-associated protein-43 and long-term potentiation in guinea pig hippocampus. Brain Res Bull 64:433-40
Cao, Z; Kemp, M D; Wang, Y et al. (2004) Cloning and identification of Rab cDNAs from Limulus polyphemus. Cell Mol Biol (Noisy-le-grand) 50:737-47
Wormley, D D; Chirwa, S; Nayyar, T et al. (2004) Inhaled benzo(a)pyrene impairs long-term potentiation in the F1 generation rat dentate gyrus. Cell Mol Biol (Noisy-le-grand) 50:715-21
Wang, Yilun; Cao, Zheng; Xu, Wei et al. (2004) Cloning and partial characterization of four plasmalemmal-associated syntaxin isoforms in Limulus. Gene 326:189-99
Cao, Z; McAdory, B S; Wang, Y et al. (2003) The chemorepellent semaphorin is expressed in the horseshoe crab, Limulus polyphemus. Cell Mol Biol (Noisy-le-grand) 49:1261-7
Chirwa, S; Mack, J; Park, R et al. (2001) An in vivo model for investigating bilateral synaptic plasticity across CA3/CA1 synapses in guinea pig dorsal hippocampus. J Neurosci Methods 110:25-30

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