Attention and effort on this computer program for consultative diagnosis in medicine have been focused during the past year on two areas primarily, (a) the development of the new CADUCEUS program, and (b) the expansion and updating of the medical knowledge base. Prototypic computer programs have been written for the operation of CADUCEUS and have been preliminarily tested. A substantial portion of the medical knowledge base (diseases of the liver and biliary tract) has been reorganized in the CADUCEUS format. The installation of a dedicated VAX computer this summer will allow these programs to be tested critically and then further work can proceed on both elements. The knowledge base in internal medicine has been expanded so that it now includes over 500 diseases and some 3,450 individual manifestations of disease. Many disease entities which were programmed some years ago have been updated. It is gratifying but not unexpected that this expansion and updating have improved the performance of INTERNIST-I. The pediatrics knowledge base has been significantly expanded also. Considerable progress has been made on an anatomy knowledge base for utilization in CADUCEUS. Progress has also been made on the reorganization of the diagnostic program to a form utilizable for educational and testing purposes by medical students and physicians. Future work will proceed along all of these lines with emphasis on the organization and refinement of the CADUCEUS diagnostic program.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Resource-Related Research Projects (R24)
Project #
3R24RR001101-08S1
Application #
3450498
Study Section
(SSS)
Project Start
1977-07-01
Project End
1986-03-31
Budget Start
1985-09-30
Budget End
1986-03-31
Support Year
8
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Sch of Business/Public Admin
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
First, M B; Soffer, L J; Miller, R A (1985) QUICK (QUick Index to Caduceus Knowledge): using the INTERNIST-1/CADUCEUS knowledge base as an electronic textbook of medicine. Comput Biomed Res 18:137-65
Masarie Jr, F E; Miller, R A; Myers, J D (1985) INTERNIST-I properties: representing common sense and good medical practice in a computerized medical knowledge base. Comput Biomed Res 18:458-79
Miller, R A; Schaffner, K F; Meisel, A (1985) Ethical and legal issues related to the use of computer programs in clinical medicine. Ann Intern Med 102:529-37