Washington University Cancer Genomics and Outcomes Research STRENGTH (Short-Term Research Education and Growth Through Hands-On Experiences) Program Background: Advances in genomics and cancer biology have transformed the treatment of patients with cancer. The new generation of trainees needs to be educated in the emerging discipline of cancer genomics. Even as our understanding of cancer genomics continues at an extraordinary pace, the costs of health care in general and cancer care, in particular, have been increasing at a level that will soon be unsustainable. The proposed Washington University Cancer Genomics and Outcomes Research STRENGTH (Short-Term Research Education and Growth Through Hands-On Experiences) Program, from now on referred to as the STRENGTH program, is uniquely tailored to educate physicians-in-training on two key aspects that are critical for cancer research today: cancer genomics and outcomes research. Goals and Objectives: The overall goal for this research education program is to develop and implement a first of its kind at Washington University (WU) in St. Louis. The STRENGTH program is designed for postdoctoral scholars (PhDs and MDs) who are still under training and interested in pursuing patient oriented cancer research.
The aims of this program are to: 1) develop and implement an innovative model internet- based educational program in genomics and outcomes research coupled with workshops and seminars 2) train 8-10 postdoctoral fellows and researchers annually over a five-year period in cancer genomics and outcomes research; 3) conduct ongoing mentoring that includes hands-on research training experiences, structured mentorship meetings and intensive career development activities; 4) evaluate all research education program components and track participants' career development over time; and 5) actively disseminate program components to encourage adoption by other individuals and institutions. Significance and Innovation: The existing cancer-related training programs target mainly undergraduate students or junior faculty physicians. There is an urgent need to develop short-term structured specialized programs targeting postdoctoral scholars still in-training (PhDs and MDs), interested in pursuing a career in patient-oriented cancer research. The STRENGTH program is highly innovative and has unique strengths: 1) It addresses the current gap in cancer genomics and outcomes research training opportunities for postdoctoral scholars in training (PhDs and MDs), referred to as postdoctoral scholars from now on; 2) It utilizes a hybrid learning model that includes web-based and face-to-face didactic training combined with hands-on research opportunities; 3) It places a strong emphasis on mentoring and career development; 4) It includes a multi- disciplinary faculty team with a proven track record in establishing successful training programs; and 5) It will be disseminated widely and can be applied to other disciplines and specialty training areas.

Public Health Relevance

This project is relevant to public health because it addresses the need to apply existing knowledge in the fields of genomics and outcomes research to reduce cancer morbidity and mortality in the population. The project will develop innovative programs to train young physicians and scientists in the application of genomics and outcomes research in the treatment and control of cancer. Upon completion, this program will provide transferable training strategies and tools that can be adapted and applied to other settings and disciplines.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Education Projects (R25)
Project #
5R25CA190190-03
Application #
9266376
Study Section
Subcommittee I - Transistion to Independence (NCI)
Program Officer
Korczak, Jeannette F
Project Start
2015-04-14
Project End
2020-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
3
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Devarakonda, Siddhartha; Govindan, Ramaswamy (2018) Targeting Resistance to Targeted Therapies: Combating a Resilient Foe. Clin Cancer Res 24:6112-6114
Nandy, Sreyankar; Mostafa, Atahar; Hagemann, Ian S et al. (2018) Evaluation of Ovarian Cancer: Initial Application of Coregistered Photoacoustic Tomography and US. Radiology 289:740-747
Sun, Lulu; Zhang, Lingxin; Krigman, Hannah R et al. (2018) p16 Immunohistochemistry Is Not Always Required For Accurate Diagnosis of Grade 2 Squamous Intraepithelial Lesions. J Low Genit Tract Dis 22:104-109
Toriola, Adetunji T; Dang, Ha X; Hagemann, Ian S et al. (2017) Increased breast tissue receptor activator of nuclear factor-?B ligand (RANKL) gene expression is associated with higher mammographic density in premenopausal women. Oncotarget 8:73787-73792
Mullen, Mary M; Divine, Laura M; Hagemann, Ian S et al. (2017) Endometrial adenosarcoma in the setting of a germline DICER1 mutation: A case report. Gynecol Oncol Rep 20:121-124