This application seeks continuation of funding for the Substance Use and HIV Prevention Research in Minority Communities program (SUHPR) at the University of California San Francisco (UCSF). This training program addresses the urgent need highlighted in NIDA PAR-13-084, the 2013 National AIDS Strategy, and the 2012 NIDA Research Report on Drug Abuse and HIV/AIDS to promote clinical prevention research and reduce health disparities in vulnerable communities where substance use is a crucial public health concern. SUHPR also aims to increase the number of scientists from diverse backgrounds who attain NIH funding by providing a research education curriculum, mentoring, and pilot study funding to early-career clinical scientists (visiting professors or VPs) to secure multiyear funding to conduct innovative health disparities research at the intersection of HIV and substance use risk.
The aims of this five-year project are to: 1) increase the capacity of VPs to conduct multidisciplinary prevention research that elucidates the links between substance use and HIV risk in underserved communities; 2) provide funding to conduct pilot clinical research that will yield data for substance-use-related presentations at national conferences and provide preliminary data for grant proposals to NIDA; 3) provide education, mentoring, and technical assistance in the development and submission of research grants to NIDA that focus on substance use, HIV prevention, and improving HIV care outcomes; and 4) engage former VPs to help expand their innovative clinical research programs targeting the intersection of HIV and substance use, leverage their experience to benefit current and future VPs, and hone their skills as independent researchers. To address aims 1-3 the SUHPR program will implement a summer program for early-career clinical scientists who have not yet obtained R01-level funding. Each VP will visit CAPS for three summers and attend seminars on HIV and substance use research, methods, and grant writing. SUHPR also includes parallel networking activities, such as attending national conferences and open access publishing. The SUHPR is structured across three consecutive six-week summer sessions. In the first summer, mentors will assist each VP to plan a pilot study. In the second summer, each VP will analyze the pilot data and draft a multiyear grant proposal that is peer reviewed. During the third summer, the VPs will obtain extensive feedback on their grant proposals, revise them, and submit them for extramural review. During the academic years between summers mentors will communicate with VPs at least monthly, supplemented by webinars and the program's custom web site. To fortify this intensive research education experience, the program will implement aim 4 by providing peer review and consultations to help VPs remain in the research pipeline and extend their programs of substance use and HIV-prevention research. We will also leverage successful former VPs for peer review with current VPs. Collectively completing specific aims 1-4 will accelerate the development of HIV and substance use health disparities research programs with high public health impact.

Public Health Relevance

Research to advance understanding of the development and progression of diseases and disabilities that contribute to minority health and other health disparities is a major goal of the National Institutes of Health's strategic research plan to reduc and ultimately eliminate health disparities. Innovative, evidence-based interventions that rely on well-researched and culturally-specific theories of human behavior are urgently needed to stem the rising tide of HIV and other sexually-transmitted infections in underserved communities and the corresponding rates of substance use and abuse. The Substance Use and HIV Prevention Research in Minority Communities research education and mentoring program aims to address this research deficit through offering seed funding to promising clinical scientists to conduct pilt studies and a mentoring infrastructure to empower these scientists to successfully apply for and receive NIDA funding to conduct rigorous, multi-year research projects in the communities most affected by these epidemics.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Education Projects (R25)
Project #
5R25DA028567-07
Application #
9103027
Study Section
Special Emphasis Panel (ZDA1)
Program Officer
Jenkins, Richard A
Project Start
2009-09-30
Project End
2020-08-31
Budget Start
2016-09-01
Budget End
2017-08-31
Support Year
7
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94118
Levine, Ethan Czuy; Martinez, Omar; Mattera, Brian et al. (2018) Child Sexual Abuse and Adult Mental Health, Sexual Risk Behaviors, and Drinking Patterns Among Latino Men Who Have Sex With Men. J Child Sex Abus 27:237-253
Muñoz-Laboy, Miguel; Martinez, Omar; Levine, Ethan C et al. (2018) Syndemic Conditions Reinforcing Disparities in HIV and Other STIs in an Urban Sample of Behaviorally Bisexual Latino Men. J Immigr Minor Health 20:497-501
Mattera, Brian; Levine, Ethan C; Martinez, Omar et al. (2018) Long-term health outcomes of childhood sexual abuse and peer sexual contact among an urban sample of behaviourally bisexual Latino men. Cult Health Sex 20:607-624
Teti, Michelle; French, Bryana; Kabel, Allison et al. (2017) Portraits of Well-Being: Photography as a Mental Health Support for Women With HIV. J Creat Ment Health 12:48-61
Washington, Thomas A; Patel, Shivan N; Meyer-Adams, Nancy (2017) Drinking Patterns and HIV Risk Behaviors Among Black and Latino Men Who Have Sex Within Los Angeles County. Am J Mens Health 11:834-844
Rodríguez Madera, Sheilla L; Díaz, Nelson Varas; Pibernus, Alíxida Ramos et al. (2017) EXPLORING THE FEASIBILITY AND ACCEPTABILITY OF BIOMARKER COLLECTION FOR HIV INFECTION AND CHRONIC STRESS AMONG TRANSWOMEN IN PUERTO RICO. Rev Puertorriquena Psicol 28:268-281
Behar, Emily; Rowe, Christopher; Santos, Glenn-Milo et al. (2017) Acceptability of Naloxone Co-Prescription Among Primary Care Providers Treating Patients on Long-Term Opioid Therapy for Pain. J Gen Intern Med 32:291-295
Muñoz-Laboy, Miguel; Martínez, Omar; Guilamo-Ramos, Vincent et al. (2017) Influences of Economic, Social and Cultural Marginalization on the Association Between Alcohol Use and Sexual Risk Among Formerly Incarcerated Latino Men. J Immigr Minor Health 19:1073-1087
Washington, Thomas Alex; Applewhite, Sheldon; Glenn, Wendell (2017) Using Facebook as a Platform to Direct Young Black Men Who Have Sex With Men to a Video-Based HIV Testing Intervention: A Feasibility Study. Urban Soc Work 1:36-52
Haley, Danielle F; Linton, Sabriya; Luo, Ruiyan et al. (2017) Public Housing Relocations and Relationships of Changes in Neighborhood Disadvantage and Transportation Access to Unmet Need for Medical Care. J Health Care Poor Underserved 28:315-328

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