A.
Specific Aims There is a critical need for trained clinical and translational researchers with appropriate cultural sensitivity and perspectives in health areas that disproportionately impact minority and underserved populations. The goal of the Clinical Research Education and Career Development (CRECD) program at Morehouse School of Medicine (MSM) is to identify highly motivated doctorally prepared candidates early in their academic career for curriculum based training and mentoring in clinical and translational research (CTR), leading to the accredited Master of Science in Clinical Research (MSCR) degree. Academic activities for the CRECD program began in July 2002: a total of 68 Phase I/MSCR degree trainees have matriculated in the program representing 124% of projected enrollment, and graduated 49 scholars including 27 junior clinical faculty from diverse clinical disciplines; 89% of the trainees are underrepresented minorities and 72% are women. CRECD scholars have published 262 peer reviewed manuscripts, submitted 487 abstracts; and competed successfully for extramural funds totaling $12,523,672.00. The CRECD program provides core curriculum and mentored research training for research programs such as the collaborative CTSA (with Emory and GA Tech), the R-CENTER as well as pre-doctoral (T32) programs. This renewal will expand the curriculum for the effective learning of core competencies in order to increase the success rates of grant awards scholars, with a goal of increasing RO1 awards.
Specific Aim 1 Expand the CRECD Phase I MSCR curriculum through collaboration with CTSA graduate degree-granting programs at MSM, Emory, and Georgia Tech and prepare diverse scholars.
Specific Aim 2 Provide new professional development experiences for junior faculty and post- doctoral scholars enrolled in CRECD Phase II and CTSA KL programs 2a. Expand the CTSA K Club to CRECD current and aspiring K awardees; 2b. Introduce team science and implementation Science workshops focused on multidisciplinary health disparities research Specific Aim 3 Partner with the National Research Mentoring Network (NRMN) to provide access to professional development and mentor training 3a. Enroll in bi-annual professional development workshops on grant writing and mock study sections to increase the success rates of CRECD and KL scholars for individual K and F awards, as well as K-R where appropriate; 3b. Implement culturally responsive mentor and mentee training and mentor certification Specific Aim 4: Evaluate the program?s impact on training of multidisciplinary leaders in health disparities research, their mastery of core competencies, their completion of didactic and experiential learning opportunities, and their career trajectories.

Public Health Relevance

(Relevance) There is a critical need for trained clinical and translational researchers with appropriate cultural sensitivity and perspectives in several health areas that disproportionately affect minority and underserved populations. The Clinical Research Education and Career Development (CRECD) in Minority Institutions (R25) at Morehouse School of Medicine program provides a funding mechanism to address these public health challenges.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Education Projects (R25)
Project #
5R25MD007589-14
Application #
9851751
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Das, Rina
Project Start
2002-09-30
Project End
2022-01-31
Budget Start
2020-02-01
Budget End
2021-01-31
Support Year
14
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Morehouse School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Huang, Yan; Leng, Tian-Dong; Inoue, Koichi et al. (2018) TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. J Biol Chem 293:14393-14406
Estape, Estela S; Quarshie, Alexander; Segarra, Barbara et al. (2018) Promoting Diversity in the Clinical and Translational Research Workforce. J Natl Med Assoc 110:598-605
Xu, Junjun; Williams-Livingston, Arletha; Gaglioti, Anne et al. (2018) A Practical Risk Stratification Approach for Implementing a Primary Care Chronic Disease Management Program in an Underserved Community. J Health Care Poor Underserved 29:202-213
Liu, Mingli; Solomon, Wesley; Cespedes, Juan Carlos et al. (2018) Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. J Neuroinflammation 15:104
Gastala, Nicole M; Wingrove, Peter M; Gaglioti, Anne H et al. (2018) The Growing Trend of Health Coaches in Team-Based Primary Care Training A Multicenter Pilot Study. Fam Med 50:526-530
Matthews, Kevin A; Xu, Wei; Gaglioti, Anne H et al. (2018) Racial and ethnic estimates of Alzheimer's disease and related dementias in the United States (2015-2060) in adults aged ?65 years. Alzheimers Dement :
Gaglioti, Anne H; Xu, Junjun; Rollins, Latrice et al. (2018) Neighborhood Environmental Health and Premature Death From Cardiovascular Disease. Prev Chronic Dis 15:E17
Hu, Guoku; Yelamanchili, Sowmya; Kashanchi, Fatah et al. (2017) Proceedings of the 2017 ISEV symposium on ""HIV, NeuroHIV, drug abuse, & EVs"". J Neurovirol 23:935-940
Liu, Mingli (2017) Letter to the Editor on ""Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL"". Stem Cell Res Ther 8:130
Westney, Gloria; Foreman, Marilyn G; Xu, Junjun et al. (2017) Impact of Comorbidities Among Medicaid Enrollees With Chronic Obstructive Pulmonary Disease, United States, 2009. Prev Chronic Dis 14:E31

Showing the most recent 10 out of 18 publications