This application is aimed at preparing physicians for independent careers in the investigation and treatment of childhood psychiatric disorders. Such programs are urgently needed. This need is based on the large number of children affected, the considerable costs to society associated with their care, the limited effectiveness of available treatment and prevention programs, the small number of physician-scientists active in the field, and the potential for significant scientific advances in the foreseeable future. This grant will make it possible for the faculty of the Yale Child Study Center, working with the American Academy of Child and Adolescent Psychiatry (AACAP) and academic leaders across the country, to refine, evaluate and disseminate model research education programs that extend from the first year of medical school through postdoctoral research training and the submission of a Career Development Award. Participants will.be encouraged to pursue advanced degrees. For Yale Medical Students, this award will support research seminars and medical student research thesis projects. This initiative builds on Yale's long-standing requirement that medical students complete a research thesis project in order to graduate. This fellowship program was initially funded by the Klingenstein Third Generation (KTG) Foundation in 2001. Based on the success of the fellowship program at Yale, the KTG Foundation funded five additional sites across the country in 2004 (Harvard, Johns Hopkins, Mt. Sinai, Stanford, and UC Davis). For postdoctoral participants entering the Integrated Child and Adult Psychiatry Research Pathway at Yale, this award will permit us to fund intensive periods of research training prior to their entering our recently renewed interdisciplinary T32 Institutional Research Training Program. A similar program is underway at the University of Colorado. There are currently nine participants between these two sister programs, with another four expected to enter in July 2006. Funds are also requested to support the national independent evaluation of both the KGT Foundation Medical Student Fellowship (at six sites) and the Integrated Research Pathway Program (at two sites).
| Leon, Jill; Hommer, Rebecca; Grant, Paul et al. (2018) Longitudinal outcomes of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). Eur Child Adolesc Psychiatry 27:637-643 |
| Abdulkadir, Mohamed; Londono, Douglas; Gordon, Derek et al. (2018) Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. Eur Arch Psychiatry Clin Neurosci 268:301-316 |
| Muhle, Rebecca A; Reed, Hannah E; Aguayo, Patricia et al. (2018) Evaluation and Management of Self-injury in a Child With a Rare Genomic Variant. JAMA Psychiatry 75:524-525 |
| Abbott, Parker W; Gumusoglu, Serena B; Bittle, Jada et al. (2018) Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness. Psychoneuroendocrinology 90:9-21 |
| Olten, Baris; Bloch, Michael H (2018) Meta regression: Relationship between antipsychotic receptor binding profiles and side-effects. Prog Neuropsychopharmacol Biol Psychiatry 84:272-281 |
| Frick, Luciana R; Rapanelli, Maximiliano; Jindachomthong, Kantiya et al. (2018) Differential binding of antibodies in PANDAS patients to cholinergic interneurons in the striatum. Brain Behav Immun 69:304-311 |
| Muhle, Rebecca A; Reed, Hannah E; Stratigos, Katharine A et al. (2018) The Emerging Clinical Neuroscience of Autism Spectrum Disorder: A Review. JAMA Psychiatry 75:514-523 |
| Beversdorf, David Q; Stevens, Hanna E; Jones, Karen L (2018) Prenatal Stress, Maternal Immune Dysregulation, and Their Association With Autism Spectrum Disorders. Curr Psychiatry Rep 20:76 |
| Brainstorm Consortium (see original citation for additional authors) (2018) Analysis of shared heritability in common disorders of the brain. Science 360: |
| Hayman, Victoria; Fernandez, Thomas V (2018) Genetic Insights Into ADHD Biology. Front Psychiatry 9:251 |
Showing the most recent 10 out of 218 publications
