Brain diseases such as Alzheimer's disease, glioma, Parkinson's disease, and amyotrophic lateral sclerosis devastate the lives of millions of patients and their families. Despite decades of research costing billions of dollars, these and other brain diseases sorely lack diagnostic tools, effective disease- modifying therapies, adequate symptomatic managements, or even well-defined mechanistic causes. These failures stand out particularly in light of incredible advances in basic scientific knowledge. Thus there is a critical need for clinicians to be involved in basic research on human brain disease since they are well suited to identify new treatments. The University of Iowa Clinical Neuroscientist Training Program is designed as a more efficient pathway to train outstanding neurology and neurosurgery residents in basic research, with the goal of increasing the percentage of trainees who continue in a long career as productive clinician-scientists.

Public Health Relevance

Physician scientists bring unique skills to scientific investigation and offer enhanced opportunities to translate basic scientific discovery to diagnosis and treatment of human disease. This program seeks to meet the need for more clinical neurologists and neurosurgeons trained in basic neuroscience.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Education Projects (R25)
Project #
2R25NS079173-06
Application #
9209519
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Korn, Stephen J
Project Start
2012-06-15
Project End
2022-06-30
Budget Start
2017-07-15
Budget End
2018-06-30
Support Year
6
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Iowa
Department
Neurology
Type
Schools of Medicine
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Serrano-Pozo, Alberto; Aldridge, Georgina M; Zhang, Qiang (2017) Four Decades of Research in Alzheimer's Disease (1975-2014): A Bibliometric and Scientometric Analysis. J Alzheimers Dis 59:763-783
Serrano-Pozo, Alberto; Sánchez-García, Manuel A; Heras-Garvín, Antonio et al. (2017) Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-? Peptide Generation In Vivo. PLoS One 12:e0170345