Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AG012467-02
Application #
2054108
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1995-05-10
Project End
2000-04-30
Budget Start
1996-05-10
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Lee, J Y; Hannun, Y A; Obeid, L M (2000) Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-alpha (TNF-alpha ) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-alpha. J Biol Chem 275:29290-8
Lee, J Y; Leonhardt, L G; Obeid, L M (1998) Cell-cycle-dependent changes in ceramide levels preceding retinoblastoma protein dephosphorylation in G2/M. Biochem J 334 ( Pt 2):457-61
Zhang, P; Liu, B; Kang, S W et al. (1997) Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2. J Biol Chem 272:30615-8
Obeid, L M; Venable, M E (1997) Signal transduction in cellular senescence. J Am Geriatr Soc 45:361-6
Venable, M E; Bielawska, A; Obeid, L M (1996) Ceramide inhibits phospholipase D in a cell-free system. J Biol Chem 271:24800-5