Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI030550-05
Application #
2065705
Study Section
Experimental Immunology Study Section (EI)
Project Start
1991-03-01
Project End
1997-02-28
Budget Start
1995-03-01
Budget End
1997-02-28
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Speck, S H; Chatila, T; Flemington, E (1997) Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene. Trends Microbiol 5:399-405
Liu, S; Liu, P; Borras, A et al. (1997) Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member. EMBO J 16:143-53
Trede, N S; Tsytsykova, A V; Chatila, T et al. (1995) Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B. J Immunol 155:902-8
Morio, T; Geha, R S; Chatila, T A (1994) Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases. Eur J Immunol 24:651-8
Mosialos, G; Hanissian, S H; Jawahar, S et al. (1994) A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1. J Virol 68:1697-705
Trede, N S; Castigli, E; Geha, R S et al. (1993) Microbial superantigens induce NF-kappa B in the human monocytic cell line THP-1. J Immunol 150:5604-13
Castigli, E; Chatila, T A; Geha, R S (1993) A protein of the AP-1 family is a component of nuclear factor of activated T cells. J Immunol 150:3284-90
Trede, N S; Chatila, T; Geha, R S (1993) Activator protein-1 (AP-1) is stimulated by microbial superantigens in human monocytic cells. Eur J Immunol 23:2129-35
Scholl, P R; Trede, N; Chatila, T A et al. (1992) Role of protein tyrosine phosphorylation in monokine induction by the staphylococcal superantigen toxic shock syndrome toxin-1. J Immunol 148:2237-41
Spertini, F; Chatila, T; Geha, R S (1992) Engagement of MHC class I molecules induces cell adhesion via both LFA-1-dependent and LFA-1-independent pathways. J Immunol 148:2045-9

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