Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI031622-05
Application #
2066613
Study Section
Virology Study Section (VR)
Project Start
1991-08-01
Project End
1997-05-31
Budget Start
1995-06-01
Budget End
1997-05-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wadsworth Center
Department
Type
DUNS #
110521739
City
Menands
State
NY
Country
United States
Zip Code
12204
Lavi, E; Kuo, L; Haluskey, J A et al. (1998) Targeted recombination between MHV-2 and MHV-A59 to study neurotropic determinants of MHV. Adv Exp Med Biol 440:543-7
Fischer, F; Stegen, C F; Koetzner, C A et al. (1998) Construction of a mouse hepatitis virus recombinant expressing a foreign gene. Adv Exp Med Biol 440:291-5
Hsue, B; Masters, P S (1998) An essential secondary structure in the 3' untranslated region of the mouse hepatitis virus genome. Adv Exp Med Biol 440:297-302
Lavi, E; Haluskey, J A; Masters, P S (1998) The pathogenesis of MHV nucleocapsid gene chimeric viruses. Adv Exp Med Biol 440:537-41
Fischer, F; Stegen, C F; Koetzner, C A et al. (1997) Analysis of a recombinant mouse hepatitis virus expressing a foreign gene reveals a novel aspect of coronavirus transcription. J Virol 71:5148-60
Fischer, F; Peng, D; Hingley, S T et al. (1997) The internal open reading frame within the nucleocapsid gene of mouse hepatitis virus encodes a structural protein that is not essential for viral replication. J Virol 71:996-1003
Hsue, B; Masters, P S (1997) A bulged stem-loop structure in the 3' untranslated region of the genome of the coronavirus mouse hepatitis virus is essential for replication. J Virol 71:7567-78
Peng, D; Koetzner, C A; Masters, P S (1995) Analysis of second-site revertants of a murine coronavirus nucleocapsid protein deletion mutant and construction of nucleocapsid protein mutants by targeted RNA recombination. J Virol 69:3449-57
Masters, P S; Peng, D; Fischer, F (1995) Mutagenesis of the genome of mouse hepatitis virus by targeted RNA recombination. Adv Exp Med Biol 380:543-9
Peng, D; Koetzner, C A; McMahon, T et al. (1995) Construction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins. J Virol 69:5475-84

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