Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI033510-04
Application #
2068558
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Pathology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Clevenger, C V; Freier, D O; Kline, J B (1998) Prolactin receptor signal transduction in cells of the immune system. J Endocrinol 157:187-97
Chang, W P; Ye, Y; Clevenger, C V (1998) Stoichiometric structure-function analysis of the prolactin receptor signaling domain by receptor chimeras. Mol Cell Biol 18:896-905
Reynolds, C; Montone, K T; Powell, C M et al. (1997) Expression of prolactin and its receptor in human breast carcinoma. Endocrinology 138:5555-60
Clevenger, C V; Plank, T L (1997) Prolactin as an autocrine/paracrine factor in breast tissue. J Mammary Gland Biol Neoplasia 2:59-68
Clevenger, C V; Thickman, K; Ngo, W et al. (1997) Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2. Mol Endocrinol 11:608-18
Chang, W P; Clevenger, C V (1996) Modulation of growth factor receptor function by isoform heterodimerization. Proc Natl Acad Sci U S A 93:5947-52
Luger, S M; Ratajczak, J; Ratajczak, M Z et al. (1996) A functional analysis of protooncogene Vav's role in adult human hematopoiesis. Blood 87:1326-34
Clevenger, C V; Ngo, W; Sokol, D L et al. (1995) Vav is necessary for prolactin-stimulated proliferation and is translocated into the nucleus of a T-cell line. J Biol Chem 270:13246-53
Clevenger, C V; Chang, W P; Ngo, W et al. (1995) Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop. Am J Pathol 146:695-705
Clevenger, C V; Medaglia, M V (1994) The protein tyrosine kinase P59fyn is associated with prolactin (PRL) receptor and is activated by PRL stimulation of T-lymphocytes. Mol Endocrinol 8:674-81

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