Identification of Lps-Induced Signalling Mechamisms

Smith, Michael F.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 7R29AI034358-02
• Application #: 2069484
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1995-07-01
• Project End: 2000-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Virginia
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 001910777
• City: Charlottesville
• State: VA
• Country: United States
• Zip Code: 22904

Publications

Jefferson, K K; Smith Jr, M F; Bobak, D A (1999) Roles of intracellular calcium and NF-kappa B in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes. J Immunol 163:5183-91

Jenkins, J K; Drong, R F; Shuck, M E et al. (1997) Intracellular IL-1 receptor antagonist promoter: cell type-specific and inducible regulatory regions. J Immunol 158:748-55

Guthridge, C J; Eidlen, D; Arend, W P et al. (1997) Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms. Mol Cell Biol 17:1118-28