Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI034472-03
Application #
2069580
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Institute for Cancer Research
Department
Type
DUNS #
872612445
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Kappes, Dietmar J; He, Xi; He, Xiao (2006) Role of the transcription factor Th-POK in CD4:CD8 lineage commitment. Immunol Rev 209:237-52
Kappes, D J; Lawrence, D M; Vaughn, M M et al. (2000) Protection of CD3 delta knockout mice from lymphocytic choriomeningitis virus-induced immunopathology: implications for viral neuroinvasion. Virology 269:248-56
Keefe, R; Dave, V; Allman, D et al. (1999) Regulation of lineage commitment distinct from positive selection. Science 286:1149-53
Dave, V P; Allman, D; Wiest, D L et al. (1999) Limiting TCR expression leads to quantitative but not qualitative changes in thymic selection. J Immunol 162:5764-74
Dave, V P; Allman, D; Keefe, R et al. (1998) HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells. Proc Natl Acad Sci U S A 95:8187-92
Dave, V P; Keefe, R; Berger, M A et al. (1998) Altered functional responsiveness of thymocyte subsets from CD3delta-deficient mice to TCR-CD3 engagement. Int Immunol 10:1481-90
Kappes, D J; Alarcon, B; Regueiro, J R (1995) T lymphocyte receptor deficiencies. Curr Opin Immunol 7:441-7