Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI034486-03
Application #
2069597
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Anderson, E L; Kobayashi, T; Iijima, K et al. (2016) IL-33 mediates reactive eosinophilopoiesis in response to airborne allergen exposure. Allergy 71:977-88
Kobayashi, Takehito; Soma, Tomoyuki; Noguchi, Toru et al. (2015) ATP drives eosinophil effector responses through P2 purinergic receptors. Allergol Int 64 Suppl:S30-6
Bartemes, Kathleen R; Kephart, Gail M; Fox, Stephanie J et al. (2014) Enhanced innate type 2 immune response in peripheral blood from patients with asthma. J Allergy Clin Immunol 134:671-678.e4
Fujisawa, Daisuke; Kashiwakura, Jun-Ichi; Kita, Hirohito et al. (2014) Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria. J Allergy Clin Immunol 134:622-633.e9
Bartemes, Kathleen R; Iijima, Koji; Kobayashi, Takao et al. (2012) IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J Immunol 188:1503-13
Matsuwaki, Yoshinori; Wada, Kota; White, Thomas et al. (2012) Alternaria fungus induces the production of GM-CSF, interleukin-6 and interleukin-8 and calcium signaling in human airway epithelium through protease-activated receptor 2. Int Arch Allergy Immunol 158 Suppl 1:19-29
Kouzaki, Hideaki; Iijima, Koji; Kobayashi, Takao et al. (2011) The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol 186:4375-87
Kephart, Gail M; Alexander, Jeffrey A; Arora, Amindra S et al. (2010) Marked deposition of eosinophil-derived neurotoxin in adult patients with eosinophilic esophagitis. Am J Gastroenterol 105:298-307
Kobayashi, Takehito; Kouzaki, Hideaki; Kita, Hirohito (2010) Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP. J Immunol 184:6350-8
Bates, Mary Ellen; Sedgwick, Julie B; Zhu, Yiming et al. (2010) Human airway eosinophils respond to chemoattractants with greater eosinophil-derived neurotoxin release, adherence to fibronectin, and activation of the Ras-ERK pathway when compared with blood eosinophils. J Immunol 184:7125-33

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