Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI034785-04
Application #
2069968
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1993-07-15
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Pharmacology
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Wang, Z; Rana, T M (1998) RNA-protein interactions in the Tat-trans-activation response element complex determined by site-specific photo-cross-linking. Biochemistry 37:4235-43
Wang, Z; Rana, T M (1997) DNA damage-dependent transcriptional arrest and termination of RNA polymerase II elongation complexes in DNA template containing HIV-1 promoter. Proc Natl Acad Sci U S A 94:6688-93
Ping, Y H; Liu, Y; Wang, X et al. (1997) Dynamics of RNA-protein interactions in the HIV-1 Rev-RRE complex visualized by 6-thioguanosine-mediated photocrosslinking. RNA 3:850-60
Song, A I; Rana, T M (1997) Synthesis of an amino acid analogue to incorporate p-aminobenzyl-EDTA in peptides. Bioconjug Chem 8:249-52
Huq, I; Rana, T M (1997) Probing the proximity of the core domain of an HIV-1 Tat fragment in a Tat-TAR complex by affinity cleaving. Biochemistry 36:12592-9
Liu, Y; Wang, Z; Rana, T M (1996) Visualizing a specific contact in the HIV-1 Tat protein fragment and trans-activation responsive region RNA complex by photocross-linking. J Biol Chem 271:10391-6
Wang, Z; Wang, X; Rana, T M (1996) Protein orientation in the Tat-TAR complex determined by psoralen photocross-linking. J Biol Chem 271:16995-8
Shah, K; Neenhold, H; Wang, Z et al. (1996) Incorporation of an artificial protease and nuclease at the HIV-1 Tat binding site of trans-activation responsive RNA. Bioconjug Chem 7:283-9
Wang, Z; Rana, T M (1996) RNA conformation in the Tat-TAR complex determined by site-specific photo-cross-linking. Biochemistry 35:6491-9
Neenhold, H R; Rana, T M (1995) Major groove opening at the HIV-1 Tat binding site of TAR RNA evidenced by a rhodium probe. Biochemistry 34:6303-9

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