Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI035175-02
Application #
2070633
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1995-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Genetics
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Koblin, Beryl A; Chesney, Margaret A; Husnik, Marla J et al. (2003) High-risk behaviors among men who have sex with men in 6 US cities: baseline data from the EXPLORE Study. Am J Public Health 93:926-32
Montagna, L G; Ivanov, M I; Bliska, J B (2001) Identification of residues in the N-terminal domain of the Yersinia tyrosine phosphatase that are critical for substrate recognition. J Biol Chem 276:5005-11
Black, D S; Bliska, J B (2000) The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulence. Mol Microbiol 37:515-27
Black, D S; Marie-Cardine, A; Schraven, B et al. (2000) The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages. Cell Microbiol 2:401-14
Weidow, C L; Black, D S; Bliska, J B et al. (2000) CAS/Crk signalling mediates uptake of Yersinia into human epithelial cells. Cell Microbiol 2:549-60
Bliska, J B (2000) Yop effectors of Yersinia spp. and actin rearrangements. Trends Microbiol 8:205-8
Palmer, L E; Pancetti, A R; Greenberg, S et al. (1999) YopJ of Yersinia spp. is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cells. Infect Immun 67:708-16
Orth, K; Palmer, L E; Bao, Z Q et al. (1999) Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. Science 285:1920-3
Palmer, L E; Hobbie, S; Galan, J E et al. (1998) YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol Microbiol 27:953-65
Black, D S; Montagna, L G; Zitsmann, S et al. (1998) Identification of an amino-terminal substrate-binding domain in the Yersinia tyrosine phosphatase that is required for efficient recognition of focal adhesion targets. Mol Microbiol 29:1263-74

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