Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI036973-03
Application #
2073529
Study Section
Special Emphasis Panel (SRC (85))
Project Start
1994-09-30
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Winglee, Kathryn; Manson McGuire, Abigail; Maiga, Mamoudou et al. (2016) Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction. PLoS Negl Trop Dis 10:e0004332
Gupta, Shashank; Tyagi, Sandeep; Bishai, William R (2015) Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model. Antimicrob Agents Chemother 59:673-6
Maiga, Mamoudou; Ahidjo, Bintou Ahmadou; Maiga, Mariama C et al. (2015) Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis. EBioMedicine 2:868-73
Dey, Bappaditya; Dey, Ruchi Jain; Cheung, Laurene S et al. (2015) A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis. Nat Med 21:401-6
Maiga, Mariama C; Ahidjo, Bintou Ahmadou; Maiga, Mamoudou et al. (2015) Roflumilast, a Type 4 Phosphodiesterase Inhibitor, Shows Promising Adjunctive, Host-Directed Therapeutic Activity in a Mouse Model of Tuberculosis. Antimicrob Agents Chemother 59:7888-90
Winglee, Kathryn; Lun, Shichun; Pieroni, Marco et al. (2015) Mutation of Rv2887, a marR-like gene, confers Mycobacterium tuberculosis resistance to an imidazopyridine-based agent. Antimicrob Agents Chemother 59:6873-81
Choi, Seong Won; Maiga, Mamoudou; Maiga, Mariama C et al. (2014) Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test. Nat Commun 5:4989
Winglee, Kathryn; Eloe-Fadrosh, Emiley; Gupta, Shashank et al. (2014) Aerosol Mycobacterium tuberculosis infection causes rapid loss of diversity in gut microbiota. PLoS One 9:e97048
Lun, Shichun; Miranda, David; Kubler, Andre et al. (2014) Synthetic lethality reveals mechanisms of Mycobacterium tuberculosis resistance to ?-lactams. MBio 5:e01767-14
Choudhary, Eira; Bishai, William; Agarwal, Nisheeth (2014) Expression of a subset of heat stress induced genes of mycobacterium tuberculosis is regulated by 3',5'-cyclic AMP. PLoS One 9:e89759

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