Nef and HIV and SIV Molecular Pathogenesis

Sawai, Earl T.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29AI038718-02
• Application #: 2075818
• Study Section: AIDS and Related Research Study Section 3 (ARRC)
• Project Start: 1995-07-01
• Project End: 2000-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of California Davis
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 094878337
• City: Davis
• State: CA
• Country: United States
• Zip Code: 95618

Publications

Sawai, E T; Hamza, M S; Ye, M et al. (2000) Pathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated Nef. J Virol 74:2038-45

Mandell, C P; Reyes, R A; Cho, K et al. (1999) SIV/HIV Nef recombinant virus (SHIVnef) produces simian AIDS in rhesus macaques. Virology 265:235-51

Khan, I H; Sawai, E T; Antonio, E et al. (1998) Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques. J Virol 72:5820-30

Sawai, E T; Khan, I H; Montbriand, P M et al. (1996) Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques. Curr Biol 6:1519-27